Results 131 to 140 of about 630,918 (284)

Performing Large‐Scale Genetic Analysis in the Bleeding Disorders Community

Haemophilia, EarlyView.
ABSTRACT Inherited bleeding disorders encompass a diverse group of conditions caused by genetic defects affecting coagulation factors, fibrinogen, von Willebrand factor, or platelet function. Despite major advances in quantitative and functional laboratory assays, a substantial diagnostic gap remains, particularly in patients with mild or atypical ...
Anna R. Blankstein, Sterre P. E. Willems, Saskia E. M. Schols, Rosanna Asselta, Gillian Lowe, Neil V. Morgan, Paula D. James   +6 more
wiley   +1 more source

Gossypiboma‐associated sarcomas in five cases

Journal of Small Animal Practice, EarlyView.
Objectives To report clinical presentation, treatment and outcome of dogs and cats diagnosed with gossypiboma‐associated sarcoma. Materials and Methods Referral centres within the United Kingdom, Europe, North America and Australia were contacted to search medical records for dogs and cats with documented gossypiboma‐associated sarcoma and included if ...
G. Thomas, L. Doeven, A. Guillén, D. Brockman, E. Herbert, S. Priestnall, J. Helm, K. Shimura, M. Simpson   +8 more
wiley   +1 more source

The Ti Plasmid‐Encoded VirJ Functions as a Lysyl‐Phosphatidylglycerol Hydrolase in Agrobacterium tumefaciens

Molecular Microbiology, EarlyView.
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz, Lina Brodskaia, Christiane Fritz, Stefanie Hebecker, Maike K. Tauchert, Jennifer Breisch, Dieter Jahn, Franz Narberhaus, Jürgen Moser, Meriyem Aktas   +9 more
wiley   +1 more source

Development of the HTRF assay to evaluate the auxin‐induced binding between TIR1 and IAA7

New Phytologist, EarlyView.
Summary Auxin plays diverse roles in plant growth and development, including sensing environmental changes. Quantifying the interaction between auxin coreceptors provides the molecular basis for cells to sense and adapt to environmental cues. Although several assays are available, a more high‐throughput method is necessary to efficiently evaluate the ...
Jekson Robertlee, Shinya Hagihara
wiley   +1 more source

ARF6 integrates auxin and gibberellin signaling to promote stone cell lignification in pear via the HB49‐MYB169 module

New Phytologist, EarlyView.
Summary Stone cells originate from secondary cell wall thickening and contain abundant lignin. Their excessive accumulation compromises pear fruit quality, yet the endogenous hormonal mechanisms governing stone cell formation remain unclear. Here, co‐expression network analysis using transcriptome data – the flesh of 206 sand pear accessions sampled at
Yanfei Shan, Shulin Chen, Jianfa Cai, Zheng Zhou, Chong Pan, Jiahao Liu, Pengfei Zheng, Cheng Li, Yueyuan Liu, Cheng Xue, Jun Wu   +10 more
wiley   +1 more source

Musical Mereology

Pacific Philosophical Quarterly, EarlyView.
ABSTRACT I develop an axiomatic system of mereology that accounts for the ways in which musical works can be said to have parts. I distinguish two fundamental modes of composition that musical works exhibit: successive composition, whereby sound events are concatenated in time, and simultaneous composition, whereby sound events occur at the same time ...
Alejandro G. Di Rienzo
wiley   +1 more source

Региональные ключевые орнитологические территории: разработка критериев, проблемы выделения КОТР и их интеграции в систему ООПТ – нижегородский опыт

Пернатые хищники и их охрана, 2018
Осуществляемая BirdLife International программа «Important Bird Areas (IBA)» – глобальный проект, направленный на выявление и охрану угодий, особо значимых для сохранения птиц на Земле.
Sergey V. Bakka, Nadezhda Yu. Kiseleva
doaj  

Poplar miR1447 Is a Negative Regulator of Disease Resistance Through the SA‐Dependent Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Although microRNA1447 (miR1447) regulates poplar responses to abiotic stress and pest infestation, how miR1447 regulates poplar immunity against pathogens and its underlying molecular mechanisms remain to be elucidated. Here, we revealed that miR1447 functioned as a negative regulator of poplar disease resistance against fungal and bacterial ...
Dandan Xiao, Kaijing Rong, Tiantian Fu, Yicheng Li, Chun Wang, Ke Zhou, Ruen Yu, Xiaoqian Yang, Yuzhang Yang, Yuanyuan Wang, Yanwei Wang, Yonglin Wang   +11 more
wiley   +1 more source

Immunohistochemical Detection of Microglia Using Iba-1 as a Marker in Health and Disease. [PDF]

Sovrem Tekhnologii Med
Guselnikova VV, Kirik OV, Sufieva DA, Razenkova VA, Beketova AA, Korzhevskii DE.   +5 more
europepmc   +1 more source

VqLecRKV.4 and VqBAK1 Modulate Grapevine Resistance to Powdery Mildew by Regulating Dynamic Balance of ROS

Plant Biotechnology Journal, EarlyView.
ABSTRACT Grapevine powdery mildew, caused by the fungal pathogen Erysiphe necator, severely impacts plant growth and berry quality. However, the grapevine receptors and molecular mechanisms underlying grapevine resistance to E. necator remain poorly understood.
Yajuan Li, Ruilin Li, Zhuoyu Liu, Kewei You, Rongxin Li, Chen Jiao, Zhenjiang Wei, Zhi Li, Yijie Zhao, Xiping Wang   +9 more
wiley   +1 more source