Results 41 to 50 of about 630,918 (284)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Fluorescent Nanosensor for Indole‐3‐Propionic Acid Detection in Gut Health Monitoring

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces a fluorescent nanosensor system with two optical modalities for detection of indole‐3‐propionic acid (IPA) gut metabolite: (1) blue‐emitting cationic conjugated polyelectrolyte (CP3) and (2) near‐infrared (NIR)‐emitting CP3‐wrapped single‐walled carbon nanotube (SWNT).
Mervin Chun‐Yi Ang   +15 more
wiley   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

open access: yesAdvanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang   +4 more
wiley   +1 more source

3D‐Printable, Honeycomb‐Inspired Tissue‐Like Bioelectrodes for Patient‐Specific Neural Interface

open access: yesAdvanced Materials, EarlyView.
3D printed MRI‐compatible tissue‐like neural electrodes tailored to individual gyral patterns. This honeycomb‐inspired printable gel electrode (HiPGE) employs a bioinspired architecture with soft hydrogels, engineered to match the softness of brain tissue.
Marzia Momin   +12 more
wiley   +1 more source

Alternative Interpretation of Sharply Rising E0 Strengths in Transitional Regions

open access: yes, 2004
It is shown that strong 0+2 -> 0+1 E0 transitions provide a clear signature of phase transitional behavior in finite nuclei. Calculations using the IBA show that these transition strengths exhibit a dramatic and robust increase in spherical-deformed ...
A. Arima   +10 more
core   +1 more source

Impact of external debt and exchange rate volatility on domestic consumption. New evidence from Pakistan

open access: yesCogent Economics & Finance, 2019
This study has examined the impact of external debt and the volatility of exchange rate on domestic consumption in Pakistan by using the yearly data (1980–2014). We apply the bounds testing approach to cointegration and error-correction modeling to check
Ameet Kumar   +3 more
doaj   +1 more source

Bulblet regeneration from ex vitro root explant in lily hybrids

open access: yesHorticultural Science, 2008
The influence of growth regulators on in vitro bulblet formation from ex vitro roots was studied in asiatic and oriental hybrids of Lilium The root segments (3-4 mm) isolated from the middle zone of 2-3 cm ex vitro root were cultured on Murashige and ...
R. Kapoor, S. Kumar, J. K. Kanwar
doaj   +1 more source

Incorporation of an indole-3 butyric acid modified clay in epoxy resin for corrosion protection of carbon steel [PDF]

open access: yes, 2008
In the present work, indole-3 butyric acid (IBA) was inserted between montmorillonite clay platelets by cation exchange. The clay treated with the organic compound (IBA-modified clay) was then dispersed in an epoxy resin at a low concentration (2 wt ...
Dantras, Eric   +6 more
core   +1 more source

Non‐Invasive Brain Targeted Delivery of Cannabidiol for Alleviating Neuroinflammatory Disease

open access: yesAdvanced Materials, EarlyView.
The glucose‐functionalized nanoparticles (GNPs) are developed for the brain‐targeted delivery of cannabidiol (CBD). GNPs bypass the blood‐brain barrier (BBB) via glucose transporter‐1 (GLUT‐1) and release CBD in response to reactive oxygen species (ROS).
Yibin Wang   +7 more
wiley   +1 more source

Stock market return predictability: Google pessimistic sentiments versus fear gauge

open access: yesCogent Economics & Finance, 2017
This study aims at comparing Google Search Volume Indices (GSVIs—including market crash and bear market) and VIX (Investor Fear Gauge Index) in terms of explaining the S&P 500 returns. The VIX is found a more robust predictor of stock market returns than
Ume Habibah   +2 more
doaj   +1 more source

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