Results 81 to 90 of about 630,918 (284)

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Diesel Exhaust Activates & Primes Microglia: Air Pollution, Neuroinflammation, & Regulation of Dopaminergic Neurotoxicity [PDF]

, 2011
BACKGROUND: Air pollution is linked to central nervous system disease, but the mechanisms responsible are poorly understood. OBJECTIVES: Here, we sought to address the brain-region-specific effects of diesel exhaust (DE) and key cellular mechanisms ...
Block, Michelle L, Duke, Laura, Johnson, Jo Anne, Kodavanti, Prasada, Kodavanti, Urmila, Levesque, Shannon, Lull, Melinda E., Stadler, Krisztian, Surace, Michael J., Taetzsch, Thomas, Wagner, Alison   +10 more
core   +1 more source

Molecularly Engineered Phenoxazinone‐Skeleton Cascade‐Activated NIR Probes for Monitoring Fe2+/Viscosity in Ferroptosis‐Mediated Parkinson's Disease

Advanced Science, EarlyView.
A series of Fe2+/viscosity cascade‐activated NIR fluorescence probes (NP1–5) are synthesized, and NP3 is selected for its optimal properties. To verify application of NP3 in ferroptosis intervention in PD, PQR NPs, is constructed by NP3 and quercetin self‐assembling.
Lixia Guo, Tao Liu, Hongfei Wang, Qi Gao, Zhaobo Yang, Zumeng Wang, Chenlong Li, Yubing Kang, Kahleong Lim, Wen Liu, Li Lu, Chengwu Zhang   +11 more
wiley   +1 more source

Initiative For Thyroid Cancer Diagnosis: Decision Support System For Anaplast Thyroid Cancer

Sukkur IBA Journal of Computing and Mathematical Sciences, 2017
Due to the high level exposure of biomedical image analysis, Medical image mining has become one of the well-established research area(s) of machine learning.
Jamil Ahmed Chandio, M. Abdul Rehman Soomrani, Attaullah Sehito, Shafaq Siddiqui   +3 more
doaj   +1 more source

Cost effective mass multiplication of Gymnema sylvestre in hydroponic system [PDF]

, 2009
Present experiment was designed with an objective to develop a cost efficient mass multiplication method for Gymnema sylvestre using hydroponic system. A plastic tub, with polyethylene cover, containing 1/10 strength of MS salts supplemented with Indole ...
Raju Karthic, Sundaram Seshadri
core   +1 more source

Ultrasound Activated Piezoelectric Dural Patches to Drive Endogenous Neural Stem Cell–Mediated Repair Traumatic Brain Injury

Advanced Science, EarlyView.
This study presents a wireless, non‐invasive strategy for neural repair by developing a biodegradable piezoelectric dural patch that, under transcranial ultrasound, generates localized electrical fields to drive endogenous neural stem cells toward neuronal differentiation and functional integration.
Pengbo Zhou, Qingyuan Wu, Yang Wu, Runzhe Huang, Wei Li, Hanjie Niu, Hongtao Sun, Huiyu Liu   +7 more
wiley   +1 more source

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Índices de calidad de habitat y macroinvertebrados en siete Cuencas del Parque Nacional Yanachaga Chemillén y su Zona de Amortiguamiento:

Revista Peruana de Biología, 2020
Se presenta la caracterización del ambiente acuático, el ecosistema ribereño y las comunidades de macroinvertebrados en siete cuencas del flanco oeste del Parque Nacional Yanachaga Chemillén (PNYCh).
Florencia Andrea Trama, Stefany Arely Salcedo Gustavson, Laetitia Demarcy, Lorena Erbure Cardozo, Bryan Alberto Jara Palomino, Felipa Elvira Muñoz Ccuro, Josué Renato Rios Alvarado, Federico Luis Sebastian Rizo Patron Viale   +7 more
doaj   +1 more source

Emerging Molecular Antiferroelectrics: Advances and Prospects

Advanced Science, EarlyView.
This review focuses on the current research progress in emerging molecular antiferroelectrics, encompassing their diverse structures, antiferroelectricity‐associated properties, and application exploration, including energy storage, electrocaloric refrigeration, and electrostriction.
Xiaoqi Li, Qianxi Wang, Xiaoyu Zhang, Yating You, Zhihua Sun, Xitao Liu, Junhua Luo   +6 more
wiley   +1 more source

Bazı Bakteri İzolatları ve Hormon Uygulamalarının Safran Crocus sativus L. Bitkisinde Korm Oluşumu ve Kimi Bitki Özelliklerine Etkisi

Journal of Agricultural Sciences, 2016
Safran, süsengiller Iridaceae familyasından ve sonbaharda çiçek açan, soğanlı bitkilerden biridir. Ekonomik değeri yüksek, tıbbı ve aromatik bitkilerden biri olan bu bitkinin üretiminin geliştirilmesinde en büyük engel tohumluk olarak kullanılan ...
Fazilet Parlakova Karagöz, Atilla Dursun, Recep Kotan, Melek Ekinci, Ertan Yıldırım, Parisa Mohammadi   +5 more
doaj   +1 more source