Results 121 to 130 of about 229,156 (278)

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Upadacitinib‐Induced Hemolysis in a Patient With Glucose‐6‐Phosphate Dehydrogenase Deficiency—A Possible Adverse Drug Reaction

Pharmacology Research & Perspectives
Glucose‐6‐phosphate‐dehydrogenase (G6PD) deficiency is a heterogenous disorder that may lead to severe hemolytic events with the ingestion of fava beans and exposure to certain drugs.
Laura Patanè, Giuseppe Costantino, Marco Muscianisi, Clara De Francesco, Anna Viola, Walter Fries   +5 more
doaj   +1 more source

The persistence of chronic opioid use in patients with inflammatory bowel disease—A nationwide cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pain is common in patients with Crohn's disease (CD) and ulcerative colitis (UC), and a substantial proportion develop chronic opioid use (COU). We examined the persistence of COU over time and identified factors predicting persistent use. Methods This nationwide Danish cohort study included patients with an initial period of COU (definition: ≥3 ...
Bente Mertz Nørgård, Caroline Theilgaard Thorarinsson, Jan Nielsen, Mette Louise Andersen, Jens Kjeldsen, Torben Knudsen, Rahul S. Dalal   +6 more
wiley   +1 more source

Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow

Journal of Inflammation Research
Xiping Liao,1,2 Hengqian Liu,3 Yuanyuan Li,1,4 Wei Zhang,1 Qian Dai,1 Haoqi Wei,5 Jianyun Zhou,1 Xia Xie,2 Hongli Zhou1 1Clinical Medical Research Center, The Second Affiliated Hospital, Army Medical University, Chongqing, People’s Republic of China ...
Liao X, Liu H, Li Y, Zhang W, Dai Q, Wei H, Zhou J, Xie X, Zhou H   +8 more
doaj  

Afro‐Amerindian cosmopolitics in environmental education: A decolonial analysis of academic discourses involving the epistemological disputes around the term sustainability

British Educational Research Journal, EarlyView.
Abstract Considering the growing calls for decolonial approaches within the scope of Climate Change and Sustainability Education (CCSE), in this research we seek to understand the meanings which have been put into circulation through research narratives on Environmental Education (EE) concluded in Latin America, regarding Afro‐Amerindian knowledges ...
Danilo Seithi Kato, Luiz Marcelo de Carvalho   +1 more
wiley   +1 more source

Observation of electron antineutrino disappearance by the Daya Bay Reactor Neutrino Experiment

, 2013
This presentation describes a measurement of the neutrino mixing parameter, sin^2(2theta_13), from the Daya Bay Reactor Neutrino Experiment. Disappearance of electron antineutrinos at a distance of ~2 km from a set of six reactors, where the reactor flux
Worcester, Elizabeth
core   +1 more source

Extra-IBD

JCR: Journal of Clinical Rheumatology, 2020
openaire   +3 more sources

Improving Medication Adherence Levels in Inflammatory Bowel Disease (IBD) Patients: A Narrative Evidence-Based Review

Patient Preference and Adherence
Obreniokibo Ibifubara Amiesimaka,1 Kristina Aluzaite,1 Rhiannon Braund,2 Michael Schultz1,3 1Gastroenterology Research Unit, Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand; 2New Zealand Pharmacovigilance ...
Amiesimaka OI, Aluzaite K, Braund R, Schultz M   +3 more
doaj  

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source