Results 141 to 150 of about 145,684 (315)
The Evolution of Health Care Utilisation and Costs for Inflammatory Bowel Disease Over Ten Years
, 2019 BACKGROUND AND AIMS Inflammatory bowel disease [IBD] places an economic strain on health systems due to expensive pharmaceutical therapy, risk of hospitalisation and surgery, and long-term monitoring.
Pillai, Nadia +14 more
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Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
, 2019 TBiologic therapies have changed the outcome of both adult and pediatric patients with Inflammatory Bowel Disease (IBD). In September 2013, the first biosimilar of infliximab was introduced into the pharmaceutical market.
Paediatric IBD Porto group of ESPGHAN
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Clinical Pharmacology &Therapeutics, EarlyView.Biologic therapies are a major and growing driver of pharmaceutical expenditure globally, with tumor necrosis factor (TNF) inhibitors among the most widely used and costly biologics. In Australia, these therapies are funded through the Pharmaceutical Benefits Scheme (PBS), where biosimilars offer lower cost alternatives; however, the long‐term public ...
Chin Hang Yiu +4 more
wiley +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
Barrier Immunity, EarlyView.ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Association of TMAO levels with indicators of ulcerative colitis activity [PDF]
Caspian Journal of Internal MedicineBackground: The diagnosis of ulcerative colitis (UC) today is limited to a small number of biomarkers. Trimethylamine-N-oxide (TMAO) is the product of reactions resulting from the degradation of dietary-free choline, phosphatidylcholine, and carnitine ...
Yelena Laryushina +4 more
doaj
, 2005 This study specifically investigates the experiences of young people, and their management of everyday living alongside the demands of Inflammatory Bowel Disease (IBD).
Gross, Harriet +2 more
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The research progress in polyethylene oxide polymer electrolytes
FlexMat, EarlyView.Polyethylene oxide (PEO) has become the mainstream matrix material for solid polymer electrolytes (SPEs) due to its excellent lithium salt complexation ability and processability. However, its high crystallinity results in low ionic conductivity at room temperature and difficulty in suppressing lithium dendrite growth, which significantly hinders the ...
Ying Wei +8 more
wiley +1 more source
Emotional distress in inflammatory bowel disease. The importance of the IBD nurse's figure.
reservedImpatto emotivo e distress emotivo nei pazienti con malattie infiammatorie croniche intestinali e l'importanza della figura dell'IBD nurse.The emotional impact and emotional distress in patients with Inflammatory bowel disease and the importance ...
BEDIN, ILARIA
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