Results 81 to 90 of about 145,684 (315)

Clinical management of severe active ulcerative colitis in the TNF-a inhibitors era

Italian Journal of Medicine, 2013
Ulcerative colitis (UC) is a chronic inflammation of the coli mucosa clinically characterized by bloody diarrhea, abdominal pain and other systemic symptoms.
Andrea Calafiore, Fernando Rizzello, Chiara Praticò, Paolo Gionchetti, Carlo Calabrese, Giuseppina Liguori, Massimo Campieri   +6 more
doaj   +1 more source

WooJenny27/IBD-SMART: IBD-SMART

<p>IBD-SMART</p ...
Zheng
core   +1 more source

The appearance of joint manifestations in the Swiss inflammatory bowel disease cohort. [PDF]

, 2019
Background/aimsExtraintestinal manifestations (EIM) involving joints, skin, eyes and liver represent an important problem in the treatment of IBD patients. The aim of this study was to identify factors that are associated with the occurrence of joint EIM
Rogler, Gerhard, Hiller, A., Nicolas Fournier, Rogler, G., Ciurea, Adrian, Butter, M., Luc Biedermann, Scharl, Michael; https://orcid.org/, Vavricka, S.R., Scharl, M., Swiss IBD Cohort Study Group, Biedermann, Luc, Stephan R Vavricka, Biedermann, L., Butter, Matthias, Hiller, Aimee, Matthias Butter, Fournier, N., Aimee Hiller, Gerhard Rogler, Fournier, Nicolas, Adrian Ciurea, Michael Scharl, Vavricka, Stephan R, Ciurea, A.   +24 more
core   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Complex therapy of IBD

, 2019
Inflammatory bowel disease (IBD) is a chronic inflammatory disease affecting the gastrointestinal tract. It is comprised of two major groups: ULCERATIVE COLITIS and CROHN’S DISEASE. The treatment and management of IBD is complex and patient specific.
Assaf, Iyad
core  

Low prevalence of behavioural and emotional problems among Swiss paediatric patients with inflammatory bowel disease

, 2013
OBJECTIVES: Whether behavioural and emotional maladjustment is more prevalent in children with inflammatory bowel disease (IBD) than in healthy controls remains controversial. The aim of this study was to assess paediatric IBD patients for problems with
Spalinger, J., Heyland, Klaas, Schibli, S., Braegger, C.P., Koller, R., Pittet, Valérie, Schäppi, Michela, Rueger, V., Koller, Rebekka, Herzog, Denise, Herzog, D., Buehr, P., Rueger, Vanessa, Braegger, Christian P, Landolt, Markus A; https://orcid.org/, Schibli, Susanne, Nydegger, Andreas, Rogler, Daniela, Swiss IBD Cohort Study Group,, Nydegger, A., Pittet, V., Spalinger, Johannes, Schäppi, M., Landolt, M.A., Landolt, Markus A, Rogler, D., Buehr, Patrick, Heyland, K.   +27 more
core   +1 more source

Multi‐Component Functionalized Bifidobacterium Longum Hydrogel for Multi‐Target Integrated Therapy of Colitis‐Associated Anxiety and Depression

Advanced Science, EarlyView.
A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang, Yujie Zhang, Jiansheng He, Shunlian Li, Qingyan Ma, Qiao Li, Yudan Zhang, Yiyang Wang, Shaobo Ma, Songyan Jin, Chune Li, Xueyong Xie, Hang Zhang, Junze Deng, Xueqin Song, Daocheng Wu, Xiancang Ma, Feng Zhu   +17 more
wiley   +1 more source

Long‐Term Outcomes After Stoma Creation in Crohn's Disease: A Retrospective Cohort Study of 422 Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Stoma creation is often required in Crohn's disease (CD), most commonly because of progressive anorectal disease. As stoma closure strongly influences long‐term quality of life and surgical decision‐making, this study evaluated the indications and long‐term outcomes of stoma creation in patients with CD.
Kentaro Nagano, Ryuichi Kuwahara, Yusuke Tomoo, Kurando Kusunoki, Yuki Horio, Kei Kimura, Kozo Kataoka, Masataka Ikeda, Motoi Uchino, Hiroki Ikeuchi   +9 more
wiley   +1 more source

The importance of the IBD audit for patients who have IBD [PDF]

Frontline Gastroenterology, 2010
We can take two different patient perspectives to the audit: a collective or national patient view and an individual or local view. While the former should be judged a success story so far, the latter view highlights the disappointment of some patients with the current inflammatory bowel disease (
openaire   +2 more sources

Lymphocyte‐C‐Reactive Protein Ratio as Promising New Marker for Predicting Surgical Site Infection in Children With Ulcerative Colitis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Surgical site infection (SSI) is a major complication after ileal pouch–anal anastomosis (IPAA) in pediatric ulcerative colitis (UC), significantly impairing quality of life. The lymphocyte‐to–C‐reactive protein ratio (LCR), a composite marker of systemic inflammation and immune/nutritional status, has emerged as a potential ...
Yuhki Koike, Koki Higashi, Yuki Sato, Yuka Nagano, Tadanobu Shimura, Takahito Kitajima, Kohei Matsushita, Yoshiki Okita, Yoshinaga Okugawa, Yuji Toiyama   +9 more
wiley   +1 more source