Results 121 to 130 of about 27,849,568 (325)

The Role of Glutamatergic and Dopaminergic Genes in Resistant Schizophrenia: A Systematic Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Psychosis is a heterogeneous disorder, with approximately one‐third of patients experiencing treatment resistance, predominantly among individuals diagnosed with Schizophrenia. Treatment‐resistant schizophrenia (TRS) may stem from a distinct biological signature, involving abnormalities in the dopaminergic and glutamatergic systems.
Maria Teresa Moreno‐Calle, Silvia Iñiguez‐Barrio, Maria Aurora Arrue, Leire Erkoreka   +3 more
wiley   +1 more source

Impaired cell surface expression and digestive function of sucrase-isomaltase gene variants are associated with reduced efficacy of low FODMAPs diet in patients with IBS-D

Gut, 2019
Recent seminal reports in GUT 1 2 have proposed an association between gene variants of intestinal sucrase-isomaltase (SI) and the onset of irritable bowel syndrome (IBS).3 An increased risk of IBS-D (diarrhoea) symptoms in individuals harbouring the ...
Diab M. Husein, H. Naim
semanticscholar   +1 more source

Decreased TESK1-mediated cofilin 1 phosphorylation in the jejunum of IBS-D patients may explain increased female predisposition to epithelial dysfunction

Scientific Reports, 2018
Disturbed intestinal epithelial barrier and mucosal micro-inflammation characterize irritable bowel syndrome (IBS). Despite intensive research demonstrating ovarian hormones modulation of IBS severity, there is still limited knowledge on the mechanisms ...
B. Rodiño-Janeiro, C. Martínez, M. Fortea, B. Lobo, M. Pigrau, Adoración Nieto, A. González-Castro, Eloísa Salvo-Romero, D. Guagnozzi, Cristina Pardo-Camacho, C. Iribarren, F. Azpiroz, C. Alonso-Cotoner, Javier Santos, M. Vicario   +14 more
semanticscholar   +1 more source

Feasibility Study of Geosynthetic Reinforced Soil Integrated Bridge Systems (GRS-IBS) in Oklahoma [PDF]

, 2016
Bridges supported on deep foundations constitute the conventional and standard construction practice. While deep foundations provide several advantages for bridges with respect to their stability and performance, they also have some important drawbacks ...
Ngo, Theresa
core  

Factors associated with complementary and alternative medicine use in Irritable Bowel Syndrome: a literature review [PDF]

, 2013
Aim: Irritable Bowel Syndrome (IBS) is a chronic functional bowel condition, which has substantial impact on quality of life and use of healthcare services.
Usher, Lee, Lafarge, Caroline, Fox, Pauline, Mitchell, Kathryn   +3 more
core   +1 more source

Decoding Barberry Root’s Therapeutic Network: A Synergistic Solution for IBS-D

Combinatorial Chemistry & High Throughput Screening
Introduction: Barberry Root (Sankezhen, SKZ), a traditional Uyghur herb from Xinjiang, China, has been shown to alleviate diarrhea-predominant irritable bowel syndrome (IBSD); however, its molecular mechanisms remain unclear.
Qi Yan, Xufei Wang, Huijiao Jiang, Xuan Zhou, Xiangwei Wu, Xueling Chen   +5 more
openaire   +2 more sources

Effect of acupuncture and its influence on visceral hypersensitivity in IBS-D patients

Medicine, 2018
Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder associated with visceral hypersensitivity. Increased expression of colonic TRPV1 and decreased expression of microRNA-199 are implicated in the pathogenesis of ...
Li-Xia Pei, Hao Chen, Jing Guo, Lu Chen, Xiao-Liang Wu, Wan-Li Xu, Shengjie Weng, EunMee Yang, Trine-Bjoerg Hammer, Jian-Hua Sun   +9 more
semanticscholar   +1 more source

The function of the gut microbiota–bile acid–TGR5 axis in diarrhea-predominant irritable bowel syndrome

mSystems
Imbalanced gut microbiota (GM) and abnormal fecal bile acid (BA) are thought to be the key factors for diarrhea-predominant irritable bowel syndrome (IBS-D), but the underlying mechanism remains unclear.
Kai Zhan, Haomeng Wu, Yongyin Xu, Kehan Rao, Huan Zheng, Shumin Qin, Yuanming Yang, Rui Jia, Weihuan Chen, Shaogang Huang   +9 more
doaj   +1 more source

Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel® in the treatment of irritable bowel syndrome with diarrhoea (IBS-D) in adults

Trials, 2019
Background Irritable bowel syndrome (IBS) with diarrhoea (IBS-D) is a common and chronic condition that can significantly impair quality of life. The emergence of new drugs for IBS-D has been slow and there is a need for new treatments, including drug ...
A. Kemppinen, C. Howell, V. Allgar, M. Dodd, J. Gregson, C. Knowles, J. Mclaughlin, P. Pandya, P. Whorwell, E. Markaryan, Y. Yiannakou   +10 more
semanticscholar   +1 more source

Evaluation of Levels of Serum IgE and Rectal Mucosal Eosinophilia in Irritable Bowel Syndrome

The Anatolian Journal of Family Medicine, 2019
INTRODUCTION[|]Irritable bowel syndrome (IBS) and food allergic reactions are common in the community and can cause symptoms similar to each other. In this study, it is aimed to evaluate serum immunglobulin E (IgE) and rectum mucosal eosinophilia levels ...
Esra Elif Akkuş, Sabah Tüzün, Kayhan Başak, Kürşat Epöztürk, Mehmet Sayıner, Mustafa Reşat Dabak   +5 more
doaj   +1 more source