Results 191 to 200 of about 27,849,568 (325)

Unconventional but effective: breaking through IBS-D clinical practice guidelines - correspondence. [PDF]

open access: yesAnn Med Surg (Lond), 2023
Shaikh OA   +5 more
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Oral Butyrate Reduces Progression of Kidney Damage in an L‐NAME‐Induced Diabetic Kidney Disease Mouse Model

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetic kidney disease (DKD) is one of the main causes of kidney failure worldwide. Interestingly, patients affected by DKD are characterised by a low abundance of gut bacteria producing short fatty acids including butyrate, which is suggested to play a role in the decline of renal function.
Maria Novella Nicese   +13 more
wiley   +1 more source

Tongxie Yaofang ameliorates IBS-D by targeting the gut microbiota-derived tryptophan metabolites and AhR signaling axis. [PDF]

open access: yesFront Microbiol
Xie X   +10 more
europepmc   +1 more source

The trimeric Shu complex in C. elegans is an ATPase that remodels RAD51 filaments in the homologous recombination‐associated DNA damage response

open access: yesThe FEBS Journal, EarlyView.
The C. elegans Shu complex (RFS‐1/RIP‐1/SWS‐1) is a DNA‐dependent ATPase that regulates RAD‐51 filaments during homologous recombination. The trimer preferentially binds 5′‐exposed DNA, remodels RAD‐51 filaments via ATP hydrolysis, and stabilizes filaments through ATP binding.
Sam Siu Hang Chu   +4 more
wiley   +1 more source

Visual, vestibular, and ocular motor changes during nitroglycerin‐triggered vestibular migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Vestibular migraine (VM) is a common cause of intermittent dizziness, but there have been no studies with provoked (induced) VM used to characterize how the vestibular and ocular (vision) systems interact. We injected 20 patients with VM with nitroglycerin to provoke an attack and used a specialized camera to record their eye ...
Maria Dolores Villar‐Martinez   +4 more
wiley   +1 more source

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