Results 21 to 30 of about 27,849,568 (325)

Involvement of mucosal flora and enterochromaffin cells of the caecum and descending colon in diarrhoea-predominant irritable bowel syndrome

BMC Microbiology, 2021
Background Accumulating evidence supports the pivotal role of intestinal flora in irritable bowel syndrome (IBS). Serotonin synthesis by enterochromaffin (EC) cells is influenced by the gut microbiota and has been reported to have an interaction with IBS.
Jingze Yang, Peng Wang, Tong Liu, Lin Lin, Lixiang Li, Guanjun Kou, Ruchen Zhou, Pan Li, Yanqing Li   +8 more
doaj   +1 more source

Co-Administration of Soy Isoflavones and Vitamin D in Management of Irritable Bowel Disease. [PDF]

PLoS ONE, 2016
The substantial characteristics of Irritable Bowel Syndrome (IBS) are associated with estrogens in women. Both soy isoflavones and vitamin D can modulate estrogen receptors in the colonic smooth muscles.
Mahsa Jalili, Azita Hekmatdoost, Homayoon Vahedi, Hossein Poustchi, Behnam Khademi, Mohsen Saadi, Maryam Zemestani, Leila Janani   +7 more
doaj   +1 more source

An Integrated Gut Microbiota and Network Pharmacology Study on Fuzi-Lizhong Pill for Treating Diarrhea-Predominant Irritable Bowel Syndrome

Frontiers in Pharmacology, 2021
Diarrhea-predominant irritable bowel syndrome (IBS-D) is one of the most common chronic functional gastrointestinal diseases with limited treatments. Gut microbiota play an important role in chronic gastrointestinal diseases.
Zhang Zhen, Zhang Zhen, Lin Xia, Huang You, Zhou Jingwei, Yang Shasha, Wei Xinyi, Lai Wenjing, Zhang Xin, Fu Chaomei   +9 more
doaj   +1 more source

Vitamin D status in pediatric irritable bowel syndrome. [PDF]

PLoS ONE, 2017
IMPORTANCE:Irritable bowel syndrome (IBS) is associated with significant morbidity in children and adolescents, and the therapeutic efficacy of available treatment options is limited.
Benjamin Udoka Nwosu, Louise Maranda, Ninfa Candela   +2 more
doaj   +1 more source

MicroRNA-29b-3p promotes intestinal permeability in IBS-D via targeting TRAF3 to regulate the NF-κB-MLCK signaling pathway

PLoS ONE, 2023
Irritable bowel syndrome with predominant diarrhea (IBS-D) is characterized by increased intestinal permeability. Previous studies have shown that the microRNA-29 gene is involved in the regulation of intestinal permeability in patients with IBS-D. NF-κB
Yong-Fu Wang, Wei Ke, Jianfeng Gan, He Zhu, Xiangyu Xie, Guodong He, Shan Liu, Yu-Sheng Huang, Hongmei Tang   +8 more
semanticscholar   +1 more source

The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis

Nutrition Journal, 2022
Background Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder involving gut-brain interactions with limited effective treatment options.
Hangkai Huang, Linjie Lu, Yishu Chen, Yan Zeng, Chengfu Xu   +4 more
doaj   +1 more source

Understanding of the Site-Specific Microbial Patterns towards Accurate Identification for Patients with Diarrhea-Predominant Irritable Bowel Syndrome

Microbiology Spectrum, 2021
Fecal microbial community could not fully represent the intestinal microbial community. However, most studies analyzing diarrhea-dominant irritable bowel syndrome (IBS-D) were mainly based on fecal samples.
Xue Zhu, Gaichao Hong, Ying Li, Pengshuo Yang, Mingyue Cheng, Lei Zhang, Yuxue Li, Lei Ji, Gangping Li, Chaoyun Chen, Chaofang Zhong, Yu Jin, Min Yang, Hanhua Xiong, Wei Qian, Zhen Ding, Kang Ning, Xiaohua Hou   +17 more
doaj   +1 more source

The multiple effects of fecal microbiota transplantation on diarrhea-predominant irritable bowel syndrome (IBS-D) patients with anxiety and depression behaviors

Microbial Cell Factories, 2021
Background Anxiety and depression are complications in Irritable bowel syndrome (IBS) patients. In this study, we recruited 18 IBS patients with mild-modest anxiety and depression behaviors, and after the screening, we defined the FMT treatment group (n =
Hao Lin, Qingqing Guo, Zhiyong Wen, Song-Lin Tan, Jie Chen, Li-Jian Lin, Pengcheng Chen, Jianquan He, Jian-Bo Wen, Ye Chen   +9 more
semanticscholar   +1 more source

Fecal Microbial Composition and Predicted Functional Profile in Irritable Bowel Syndrome Differ between Subtypes and Geographical Locations

Microorganisms, 2023
Increasing evidence suggests a microbial pathogenesis in irritable bowel syndrome (IBS) but the relationship remains elusive. Fecal DNA samples from 120 patients with IBS, 82 Mexican (IBS-C: n = 33, IBS-D: n = 24, IBS-M: n = 25) and 38 British (IBS-C: n =
Jose F. Garcia-Mazcorro, Mercedes Amieva-Balmori, Arturo Triana-Romero, Bridgette Wilson, Leanne Smith, Job Reyes-Huerta, Megan Rossi, Kevin Whelan, Jose M. Remes-Troche   +8 more
doaj   +1 more source

Review Article: Current and future treatment approaches for IBS with diarrhoea (IBS‐D) and IBS mixed pattern (IBS‐M)

Alimentary Pharmacology and Therapeutics, 2021
Irritable bowel syndrome‐diarrhoea (IBS‐D) and IBS‐mixed stool pattern (IBS‐M) are disorders of gut‐brain interaction characterised by abdominal pain associated with diarrhoea or both diarrhoea and constipation respectively.
Judy W. Nee, A. Lembo
semanticscholar   +1 more source