Results 1 to 10 of about 142,129 (337)
Safety of ibuprofen in infants younger than six months: A retrospective cohort study. [PDF]
PLoS ONE, 2018 OBJECTIVE:We hypothesized (1) that gastrointestinal (GI) and renal adverse events (AE) would occur more often in infants first prescribed ibuprofen before rather than after six months of age and (2) that ibuprofen would be associated with more adverse ...
Paul Walsh +2 more
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In-vitro diffusion study of ibuprofen--cyclodextrin inclusion complex nanogel [PDF]
Pharmaciana, 2021 The inclusion complex is one way to enhance active substance solubility, affecting medicine dissolution and penetration. The inclusion complex is formed by utilizing b-cyclodextrin as the host of the active compounds.
Fitrianti Darusman +4 more
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Effect of the type of amino acid on the biodegradation of ibuprofen derivatives [PDF]
Archives of Environmental Protection, 2023 Water pollution caused by anthropogenic activity is a huge environmental problem. Huge amounts of consumed medicinal substances cause them to get into the environment.
Paula Elżbieta Ossowicz-Rupniewska +5 more
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Ibuprofen Degradation and Associated Bacterial Communities in Hyporheic Zone Sediments
Microorganisms, 2020 Ibuprofen, a non-steroidal anti-inflammatory pain reliever, is among pharmaceutical residues of environmental concern ubiquitously detected in wastewater effluents and receiving rivers.
Cyrus Rutere +4 more
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Pain and Therapy, 2020 Introduction Ibuprofen acid is poorly soluble in the stomach, thus reaching maximum plasma levels at approximately 90 min post-dose. Ibuprofen lysinate has been developed to accelerate absorption of ibuprofen to shorten the time to analgesic efficacy ...
Ján Kyselovič +3 more
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Scientific Reports, 2021 Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in ...
Shuchita Tiwari +5 more
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Clinical safety of ibuprofen in pediatric practice
Zdorovʹe Rebenka, 2021 The article presents a review of the literature on the side effects of ibuprofen in children. The international guidelines recommend ibuprofen as an antipyretic and analgesic drug in pediatrics. The drug is characterized by a high profile of efficacy and
T.P. Borysova
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Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans. [PDF]
, 2016 Ventilatory acclimatization to hypoxia is a time-dependent increase in ventilation and the hypoxic ventilatory response (HVR) that involves neural plasticity in both carotid body chemoreceptors and brainstem respiratory centers.
Antonova, Julie +7 more
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Ibuprofen-loaded calcium phosphate granules : combination of innovative characterization methods to relate mechanical strength to drug location [PDF]
, 2010 This paper studies the impact of the location of a drug substance on the physicochemical and mechanical properties of two types of calcium phosphate granules loaded with seven different contents of ibuprofen, ranging from 1.75% to 46%.
Ahola +44 more
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Continuous Melt Granulation for Taste-Masking of Ibuprofen
Pharmaceutics, 2021 Taste-masking of drugs, particularly to produce formulations for pediatric patients, can be challenging and require complex manufacturing approaches. The objective of this study was to produce taste-masked ibuprofen granules using a novel process, twin ...
Seth P. Forster, David B. Lebo
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