Results 1 to 10 of about 16,316 (226)

An evolutionary functional genomics approach identifies novel candidate regions involved in isoniazid resistance in Mycobacterium tuberculosis

open access: yesCommunications Biology, 2021
Victoria Furió et al. apply functional genomics and evolutionary analyses to the study of antibiotic resistance in tuberculosis. Focusing on isoniazid resistance and using genomic data from clinical strains, they identify novel candidate genes with ...
Victoria Furió   +5 more
doaj   +1 more source

Infectious bronchitis corona virus establishes productive infection in avian macrophages interfering with selected antimicrobial functions. [PDF]

open access: yesPLoS ONE, 2017
Infectious bronchitis virus (IBV) causes respiratory disease leading to loss of egg and meat production in chickens. Although it is known that macrophage numbers are elevated in the respiratory tract of IBV infected chickens, the role played by ...
Aruna Amarasinghe   +7 more
doaj   +1 more source

Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction

open access: yeseLife, 2021
Retinoic acid (RA) is an essential signaling molecule for cardiac development and plays a protective role in the heart after myocardial infarction (MI).
Fabio Da Silva   +9 more
doaj   +1 more source

Asymmetric activity of NetrinB controls laterality of the Drosophila brain

open access: yesNature Communications, 2023
Brain asymmetry is widespread across species, but its function remains poorly understood. Here, the authors show that the Netrin axon guidance pathway is involved in building an asymmetric neural circuit important for long-term memory in Drosophila.
F. Lapraz   +8 more
doaj   +1 more source

The effect of using several infectious bronchitis vaccines on the expression of TLR3 in the broiler trachea and kidney [PDF]

open access: yesIraqi Journal of Veterinary Sciences
The poultry sector is a relatively recent yet rapidly growing industry, having been established in the early twentieth century, it provides a protein source for the human population.
Ammar M. Al-AAlim, Nashwan Kareem
doaj   +1 more source

Identification of Human Breast Adipose Tissue Progenitors Displaying Distinct Differentiation Potentials and Interactions with Cancer Cells

open access: yesBiomedicines, 2022
Breast adipose tissue (AT) participates in the physiological evolution and remodeling of the mammary gland due to its high plasticity. It is also a favorable microenvironment for breast cancer progression.
Pascal Peraldi   +4 more
doaj   +1 more source

GABA signaling stimulates α-cell-mediated β-like cell neogenesis

open access: yesCommunicative & Integrative Biology, 2017
Diabetes is a chronic and progressing disease, the number of patients increasing exponentially, especially in industrialized countries. Regenerating lost insulin-producing cells would represent a promising therapeutic alternative for most diabetic ...
Tiziana Napolitano   +11 more
doaj   +1 more source

Evaluation of protective immunity in chickens vaccinated with combined IB H120/D274 and IB H120 against IS/1494/06 in Iran [PDF]

open access: yesArchives of Razi Institute
Infectious bronchitis virus (IBV) has a variety of serotypes that cause many problems in the poultry industry. Two H120 and H120-D274 live vaccines were evaluated against strain IS/1494/06 (variant 2) infectious bronchitis virus challenge.
Alireza Eshaghniya   +3 more
doaj   +1 more source

Impact of age and pre-existing immunity on the induction of human antibody responses against influenza B viruses

open access: yesHuman Vaccines & Immunotherapeutics, 2019
Pre-existing immunity to influenza is dependent on a number of factors and can vary greatly within and across influenza subtypes. In this study, volunteers (aged 18–85 years) were vaccinated with split, inactivated FluzoneTM in four consecutive influenza
Michael A. Carlock   +8 more
doaj   +1 more source

Infectious bronchitis virus variants in chickens: evolution, surveillance, control and prevention

open access: yesAustral Journal of Veterinary Sciences, 2021
Infectious bronchitis is a disease of the upper respiratory tract of chickens caused by a Gammacoronavirus (infectious bronchitis virus, IBV). Severe economic losses are caused by IBV due to a reduction in egg production and/or egg quality in layers in ...
Rodrigo A. Gallardo
doaj   +1 more source

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