Results 151 to 160 of about 159,080 (332)
目的利用小片段干扰RNA(siRNA)在肝癌细胞内诱导RNA干扰(RNAi),抑制细胞间粘附分子-1(ICAM-1)基因表达,在体外进行RNAi对肝癌治疗的实验研究。方法根据ICAM-1基因设计shRNA片断,构建pGenesil-1/ICAM-1表达载体,转入E.coli菌,并用Lipofectamine tm2000转染HepG2细胞,通过MTT方法检测细胞活性状态,应用免疫组织化学的方法检测肝癌细胞中ICAM-1基因蛋白质表达抑制情况。结果本实验已成功构建了针对ICAM-1基因的pGenesil ...
廖维甲 +5 more
doaj
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
CD99 (MIC2) regulates the LFA-1/ICAM-1-mediated adhesion of lymphocytes, and its gene encodes both positive and negative regulators of cellular adhesion. [PDF]
Ji‐Sook Hahn +11 more
openalex +1 more source
Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee +9 more
wiley +1 more source
Background Although VCAM‐1 (vascular cell adhesion molecule‐1) and ICAM‐1 (intercellular adhesion molecule‐1) have been associated with incident heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF), the associations of VCAM‐
Daniel T. Mathew +7 more
doaj +1 more source
Expression of intercellular adhesion molecule-1 (ICAM-1) in benign naevi and malignant melanomas.
Nienke L. Hansen +6 more
openalex +2 more sources
Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions [PDF]
Bernadett Szilágyi +9 more
openalex +1 more source
This study found that reduced HDL‐C correlates with impaired RV systolic function and RA strain, highlighting a mechanistic link between lipid abnormalities and right heart remodelling. Additionally, decreased HDL‐C and LDL‐C were identified as independent mortality predictors in precPH patients. Integrating lipid parameters into ESC and ESC‐CMR models
Jiajun Guo +14 more
wiley +1 more source
High Levels of TNF, Soluble TNF Receptors, Soluble ICAM-1, and IFN-γ, but Low Levels of IL-5, Are Associated with Hepatosplenic Disease in Human Schistosomiasis Mansoni [PDF]
Joseph K. Mwatha +10 more
openalex +1 more source

