Results 261 to 270 of about 21,323,950 (308)
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Journal of Oral Pathology and Medicine, 1996
Differences in expression of intercellular adhesion molecule‐1 (ICAM‐1) and ICAM‐1 mRNA levels were studied in cultured skin and oral keratinocytes before and after stimulation with different pro‐inflammatory cytokines. Basal expression of ICAM‐1 was undetectable on skin keratinocytes but oral keratinocytes expressed ICAM‐1 at high levels.
M H Thornhill
exaly +3 more sources
Differences in expression of intercellular adhesion molecule‐1 (ICAM‐1) and ICAM‐1 mRNA levels were studied in cultured skin and oral keratinocytes before and after stimulation with different pro‐inflammatory cytokines. Basal expression of ICAM‐1 was undetectable on skin keratinocytes but oral keratinocytes expressed ICAM‐1 at high levels.
M H Thornhill
exaly +3 more sources
ICAM-1 signaling in endothelial cells
Pharmacological Reports, 2009Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines.
Charlotte, Lawson, Sabine, Wolf
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Sequence and expression of rat ICAM-1
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1992We have isolated cDNA clones-coding for rat intercellular adhesion molecule-1 (RICAM-1) from a cDNA library constructed from rat Ax cells stimulated with IL-1 beta using the mouse ICAM-1 cDNA as a hybridization probe. The RICAM-1 sequence shows 79.1% homology with mouse ICAM-1 and 55.6% homology with human ICAM-1 at the nucleic acid level.
Y, Kita +5 more
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Role of ICAM-1 in antigen presentation demonstrated by ICAM-1 defective mutants.
The Journal of Immunology, 1990Abstract We report a methodology for selecting APC with mutations that have impaired their ability to present Ag to T cells. A20 B lymphoblastoid cells were mutagenized and then repeatedly cocultured with murine T-T hybridomas in the presence of specific Ag.
L H, Dang +4 more
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Circulating forms of intercellular adhesion molecule (ICAM)-1 in mice lacking membranous ICAM-1
Blood, 2000Mice deficient in intercellular adhesion molecule-1 (ICAM-1), lacking membranous ICAM-1, show a normal development but abnormalities of inflammatory and immune functions. Although the membrane-bound form of ICAM-1 is not detectable in the mutant strain, circulating ICAM-1 (cICAM) is present in serum from ICAM-1-deficient mice in similar amounts as in ...
N K, van Den Engel +4 more
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Role of the Adhesion Molecule ICAM-1 in Asthma
Journal of Asthma, 1995Cells need to interact with one another for the inflammatory response to occur. The intercellular adhesion molecule-1 (ICAM-1), a member of the immunoglobulin supergene family, plays an important role in inflammation, and circulating ICAM-1 has been reported to be elevated in patients with some inflammatory disorders.
B B, Ceyhan +3 more
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Cellular Immunology, 1990
We have previously reported that stimulation of human fibroblasts (FB) with interferon-gamma (IFN-gamma) leads to their increased adhesiveness for resting peripheral blood T lymphocytes. With the use of blocking monoclonal antibodies, we determined that intercellular adhesion molecule-1 (ICAM-1) and its T cell ligand, lymphocyte function-associated ...
T H, Piela, J H, Korn
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We have previously reported that stimulation of human fibroblasts (FB) with interferon-gamma (IFN-gamma) leads to their increased adhesiveness for resting peripheral blood T lymphocytes. With the use of blocking monoclonal antibodies, we determined that intercellular adhesion molecule-1 (ICAM-1) and its T cell ligand, lymphocyte function-associated ...
T H, Piela, J H, Korn
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Regulation of ICAM-1 Expression in Mouse Macrophages
Inflammation, 2000In a mouse model of silica (SI) induced lung injury, SI exposure increases expression of intercellular adhesion molecule-1 (ICAM-1) on lung (alveolar/interstitial) macrophages and alveolar type II epithelial cells. To investigate the regulation of SI induced ICAM-1 expression on mouse macrophages, freshly isolated macrophages (alveolar, peritoneal) and
A K, Hubbard, C, Giardina
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Circulating ICAM-1 in Alcoholic Liver Cirrhosis
International Archives of Allergy and Immunology, 2009The intercellular adhesion molecule 1 (ICAM-1) level in the serum of patients with alcoholic liver cirrhosis was measured using a sandwich enzyme-linked immunosorbent assay. Circulating ICAM-1 was significantly elevated in the sera of all 19 patients as compared with normal healthy subjects. There was no correlation with the Child grade of the disease,
Y, Mándi, I, Nagy
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Circulating ICAM-1 Is Increased in Septic Shock
American journal of respiratory and critical care medicine, 1995Abstract Adhesion molecules play a critical role in the interaction of circulating neutrophils with vascular endothelium during inflammation. Increased quantities of soluble, circulating intercellular adhesion molecule-1 (cICAM-1) are present in various inflammatory conditions.
C N, Sessler +6 more
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