Results 271 to 280 of about 159,080 (332)

T Cell/Mast Cell Crosstalk in the Skin of Patients Suffering From Immune‐Mediated Diseases, Focusing on Chronic Spontaneous Urticaria

Clinical and Translational Allergy, Volume 16, Issue 1, January 2026.
ABSTRACT The crosstalk between immune cells in skin lesions of numerous immune‐mediated diseases such as atopic dermatitis, psoriasis and other T cell mediated is fundamental for understanding the pathogenesis and treating these diseases. The mechanisms by which most activated immune cells such as T cells, mast cells, and neutrophils are shifted from ...
Elias Toubi, Raeda Mubariki, Zahava Vadasz   +2 more
wiley   +1 more source

DNA Methyltransferase Inhibition Upregulates the Costimulatory Molecule ICAM-1 and the Immunogenic Phenotype of Melanoma Cells. [PDF]

JID Innov
Cereghetti ASP, Turko P, Cheng P, Benke S, Al Hrout A, Dzung A, Dummer R, Hottiger MO, Chahwan R, Ferretti LP, Levesque MP.   +10 more
europepmc   +1 more source

Modifications of Microvascular EC Surface Modulate Phototoxicity of a Porphycene anti-ICAM-1 Immunoconjugate; Therapeutic Implications

, 2013
Elisabet Rosàs, Pablo Santomá, Miquel Duran‐Frigola, Bryan Hernandez, Maria C. Llinàs, Rubén Ruiz‐González, Santi Nonell, David Sánchez‐García, Elazer R. Edelman, Mercedes Balcells   +9 more
openalex   +1 more source

Long non‐coding RNA lncAPAT promotes atherosclerotic plaque instability by targeting ribosomal protein L22

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
LncAPAT interacted with the promoter region of RPL22 to inhibit RPL22 transcriptional activity and increase the expression of MCP‐1, thereby contributing to plaque instability. Abstract Background Long non‐coding RNAs (lncRNAs) regulate macrophage inflammation and atherosclerotic plaque stability, but mechanisms need comprehensive investigations ...
Rongxia Li, Qiyue Zhang, Yu Chen, Shuting Wang, Shuang Han, Adalaiti Kamili, Yixuan Zhong, Shujun Yang, Weili Zhang   +8 more
wiley   +1 more source

Serum lncRNA ITGB2-AS1 and ICAM-1 as novel biomarkers for rheumatoid arthritis and osteoarthritis diagnosis. [PDF]

BMC Med Genomics
Selim AM, Elsabagh YA, El-Sawalhi MM, Ismail NA, Senousy MA.   +4 more
europepmc   +1 more source

Circulating markers of inflammation are not elevated in the early development of insulin resistance

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1569-1572, February 2026.
Dominik Tischer, Sarah J. Blackwood, Marjan Pontén, Marcus Moberg, Abram Katz   +4 more
wiley   +1 more source

Targeting neutrophil‐driven immunosuppression: A strategy to overcome immune checkpoint inhibitor resistance

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
TANs drive ICI resistance via antitumour immune remodelling, angiogenesis promotion, and elevation of tumour mutation burden Neutrophil biomarkers (e.g., NLR, TAN abundance) show strong predictive value for ICI response and prognosis. Targeting TAN recruitment, polarization, function and NETosis represents a promising strategy to overcome ICI ...
Ying Ning, Ke Lei, Xinyan Gao, Yan Kong, Yuping Shan, Tian Tian, Zhumei Cui, He Ren   +7 more
wiley   +1 more source

Bevacizumab in ovarian cancer: Clinical data and predictive and prognostic biomarkers

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Evidence supporting bevacizumab in ovarian cancer and predictive biomarkers: highlighting opportunities to improve patient selection and advance personalised treatment strategies. Abstract Angiogenesis, driven by the vascular endothelial growth factor (VEGF)/VEGFR signalling axis under hypoxic conditions, is one of the hallmarks of ovarian cancer (OC),
Maria Rosaria Lamia, Erica Perri, Gustavo Baldassarre, Sandro Pignata, Chiara D'Alessio, Davide Limongello, Francesca Basso‐Valentina   +6 more
wiley   +1 more source

Circular RNAs as Biomarkers and Therapeutic Targets in Diabetic Cardiovascular Complications

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
This graphic abstract elaborates on the recent mechanism of circular RNAs (circRNAs) in the pathogenesis, diagnosis and treatment of diabetic cardiovascular complications. Diabetes mellitus induces oxidative/inflammatory stress, followed by endothelial dysfunction and leads to micro‐/macro‐vascular complications.
Shreya Singh Beniwal, Yujin Jeong, Akash Rawat, Mahmoud Einieh, Kashyapi Patil, Rafael Everton Assunção Ribeiro da Costa, Pulkit Saini, Kamal Yousef Ghazal, Abhijeet Kumar, Ayush Dwivedi, Anuja Anil Mandavkar   +10 more
wiley   +1 more source

Large soluble CD18 complexes with exclusive ICAM-1-binding properties are shed during immune cell migration in inflammation. [PDF]

J Transl Autoimmun
Ferapontov A, Mellemkjær A, McGettrick HM, Vorup-Jensen T, Kragstrup TW, Juul-Madsen K.   +5 more
europepmc   +1 more source