Results 281 to 290 of about 159,080 (332)

Tirzepatide and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications for Heart Failure Management

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Integrated framework for tirzepatide in HFpEF management. Through metabolic, haemodynamic, structural and anti‐inflammatory pathways, tirzepatide modifies the disease trajectory of HFpEF, leading to improvements in symptoms, functional capacity and reduction in HF events.
Hamza A. Abdul‐Hafez   +9 more
wiley   +1 more source

Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley   +1 more source

Human rhinovirus 16 induces an ICAM-1-PKR-ATF2 axis to modulate macrophage functions. [PDF]

open access: yesJ Virol
Faure-Dupuy S   +4 more
europepmc   +1 more source

Recent Advances in the Bioactive Compounds of Prunes (Prunus domestica L.) and Their Health Benefits

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
Prunes (Prunus domestica L.) are a functional food rich in diverse bioactive compounds, including polyphenols (such as chlorogenic acid and anthocyanins), polysaccharides, and sorbitol.This review comprehensively synthesizes current research on the nutritional composition and biological activities of prunes, highlighting their multifaceted health ...
Luyang Han   +10 more
wiley   +1 more source

Evaluation of Total Serum IgE Level and Associated Factors in Asthmatic Patients at the University of Gondar Hospital, Northwest Ethiopia: A Comparative Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Asthma is a chronic respiratory disorder with both genetic and environmental underlying risk factors. Allergic asthma, the most prevalent kind, is mostly ascribed to aberrant T helper type 2 (Th2) inflammation and is brought on by allergens.
Ayenew Assefa   +2 more
wiley   +1 more source

Bifenthrin Under Scrutiny: Revisiting Toxicological Evidence Amid Regulatory Gaps

open access: yesJournal of Applied Toxicology, Volume 46, Issue 1, Page 61-77, January 2026.
ABSTRACT Despite growing health concerns, bifenthrin (BF) remains widely used for controlling agricultural and residential pests. However, different perspectives on its toxicological profile and regulatory framework warrant a revisit and update on BF regulation towards a robust risk‐safety assessment.
Caroline V. L. Moreira   +10 more
wiley   +1 more source

Tumor-intrinsic role of ICAM-1 in driving metastatic progression of triple-negative breast cancer through direct interaction with EGFR. [PDF]

open access: yesMol Cancer
Kang JH   +13 more
europepmc   +1 more source

A novel form of integrin dysfunction involving beta 1, beta 2, and beta 3 integrins [PDF]

open access: yes, 2003
Hogg, N   +6 more
core  

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