Results 11 to 20 of about 7,149 (225)
Icariin Metabolism by Human Intestinal Microflora [PDF]
Molecules, 2016 Icariin is a major bioactive compound of Epimedii Herba, a traditional oriental medicine exhibiting anti-cancer, anti-inflammatory and anti-osteoporosis activities.
Hailong Wu, Mihyang Kim, Jaehong Han
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Icariin promotes osteogenic differentiation by upregulating alpha-enolase expression
Biochemistry and Biophysics Reports, 2023 Osteogenic differentiation is a crucial biological process for maintaining bone remodelling. Aerobic glycolysis is the main source of energy for osteogenic differentiation.
Dingbang Xie +8 more
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Effects of Icariin on Reproductive Functions in Male Rats [PDF]
Molecules, 2014 The present study investigated the effects and potential mechanism(s) of action of icariin on the reproductive functions of male rats. Adult rats were treated orally with icariin at doses of 0 (control), 50, 100, or 200 mg/kg body weight for 35 ...
Maoxin Chen +3 more
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Microbial transformation of icariin and its derivatives
Natural Product Research, 2021 Microbial transformation is an important tool to perform selective conversion of compounds to derivatives which are difficult to produce synthetically. In order to obtain icariside II and icaritin, the active components in Herba Epimedii in vivo, biotransformation studies using microbes as biocatalysts were carried out. Icariside II (2) and icaritin (3)
Fubo, Han, Ji Hye, Kim, Ik-Soo, Lee
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Icariin Research Trends: Bibliometric Analysis
Jurnal Penelitian Pendidikan IPA, 2023 Icariin is a compound with various pharmacological effects, such as anti-osteoporosis, cardiovascular protection, anti-inflammatory, antitumor, immunoprotection, and sexual dysfunction improver. Over the past decades, several publications and literatures have studied the compound and its potential effects.
Septiana Indratmoko +3 more
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mPEG-icariin nanoparticles for treating myocardial ischaemia [PDF]
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Icariin (ICA), a major active ingredient from Chinese medicine, has unique pharmacological effects on ischaemic heart disease. However, its hydrophobic property limits its administration and leads to poor efficacy. This work aimed to change its hydrophobic property and improve the treatment efficacy.
Yongqiang Zheng +9 more
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Neuroinflammation and Its Resolution: From Molecular Mechanisms to Therapeutic Perspectives [PDF]
, 2020 Neuroinflammation, the complex immune response of the central nervous system (CNS), when sustained, is a common denominator in the etiology and course of all major neurological diseases, including neurodevelopmental, neurodegenerative, and psychiatric ...
Berwian +11 more
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Rapid Structural Analysis of Natural Products Using MicroED. [PDF]
SmallThe cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Lin J, Paz O, Unge J, Gonen T.
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PLGA scaffold carrying icariin to inhibit the progression of osteoarthritis in rabbits [PDF]
Royal Society Open Science, 2019 Icariin, the main effective component extracted from epimedium, has been shown to stimulate osteogenic differentiation and bone formation and to increase synthesis of the cartilage extracellular matrix. However, there has been little study on the effects
Chang Fu Zhao +5 more
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Icariin Attenuates Amyloid-β (Aβ)-Induced Neuronal Insulin Resistance Through PTEN Downregulation
Frontiers in Pharmacology, 2020 Neuronal insulin resistance is implicated in neurodegenerative diseases. Icariin has been reported to improve insulin resistance in skeletal muscle cells and to restore impaired hypothalamic insulin signaling in the rats with chronic unpredictable mild ...
Xiaomei Zou +11 more
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