Results 141 to 150 of about 6,388,732 (302)

Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project

, 2019
Background: The clinical effectiveness of primary prevention implantable cardioverter defibrillator (ICD) therapy is under debate. It is urgently needed to better identify patients who benefit from prophylactic ICD therapy.
EU-CERT-ICD Study Investigators
core  

Development and psychometric evaluation of the Personality Disorder Severity ICD-11 (PDS-ICD-11) Clinician-Rating Form [PDF]

No clinician-rating tool has formally been developed to assess the ICD-11 model of personality disorder (PD) severity. We therefore developed and evaluated the 14-item personality disorder Severity ICD-11 (PDS-ICD-11) Clinician-Rating Form.
Brown, Tiffany A., Bach, Bo, Brown, Tiffany A, Sellbom, Martin   +3 more
core   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Belastungsbezogene Störungen in der ICD-11 [PDF]

Hintergrund und Methode Die 11. Version der Internationalen Statistischen Klassifikation der Krankheiten und verwandter Gesundheitsprobleme (ICD-11) hat im Bereich der psychischen Störungen diverse Neuerungen implementiert, wie z. B.
Eberle, David J; https://orcid.org/, Maercker, Andreas; https://orcid.org/   +1 more
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

The International Depression Questionnaire (IDQ) and International Anxiety Questionnaire (IAQ): Validation of brief ICD-11 measures for depression and generalised anxiety disorder

Background: The 11th revision of the International Classification of Diseases (ICD-11) introduced revised diagnostic criteria for a Depressive Episode (DE) and Generalised Anxiety Disorder (GAD).
Semm, Anamaria, Karatzias, Thanos, Schäflein, Eva, Knefel, Matthias, Tschöke, Stefan, Shevlin, Mark, Biedermann, Sarah V., Hyland, Philip, Kratzer, Leonhard, König, Julia, Schröder, Johanna   +10 more
core  

ICD-9 and ICD-10 codes for pulmonary and extrapulmonary TB.

ICD-9 and ICD-10 codes for pulmonary and extrapulmonary TB.
Teresa Pedraz (17720654), Maria C. Vazquez (17720660), Rosa Cano (17720666), Zaida Herrador (635669), Oriana Ramírez-Rubio (17720663), Laura Herrera (17720657)   +5 more
core   +1 more source

ICD-11: WHO eröffnet Kommentierungsphase

, 2016
Die WHO hat jüngst bei ihrer Revision Conference in Tokio die revidierte Internationale Klassifikation der Krankheiten (ICD-11) vorgestellt. Sie soll 2018 fertiggestellt und verabschiedet werden.
Müller, W
core   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source