Results 31 to 40 of about 16,008 (226)

Indoor radon in houses built on gravel and sand deposits in southern Finland [PDF]

open access: yesBulletin of the Geological Society of Finland, 1993
Studies by the Finnish Centre for Radiation and Nuclear Safety (STUK) have shown that, in Finland, indoor radon concentrations are almost twice as high in houses built on sand or gravel as in houses built on other soil types. The aim of this study was to
K.-L. Hutri, I. Mäkeläinen
doaj   +1 more source

Measuring currents, ice drift, and waves from space: the Sea surface KInematics Multiscale monitoring (SKIM) concept [PDF]

open access: yesOcean Science, 2018
We propose a satellite mission that uses a near-nadir Ka-band Doppler radar to measure surface currents, ice drift and ocean waves at spatial scales of 40 km and more, with snapshots at least every day for latitudes 75 to 82°, and every few days for ...
F. Ardhuin   +29 more
doaj   +1 more source

Late Pleistocene glaciation and retreat of ice sheet on the shelf of the South Orkney Plateau, West Antarctica

open access: yesЛëд и снег, 2021
The research aims to provide insight into reconstruction of the Late Pleistocene glaciations and ice retreat that followed the Last Glacial Maximum. The study is based on multi-channel seismic profiling and multibeam survey conducted on the shelf during ...
G. L. Leitchenkov, E. A. Bazhenova
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Health Care Use Among Patients Presenting to Emergency Department for Gout Flares in Ontario, Canada: A Population‐Based Health Systems Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We characterized emergency department (ED) gout visits and identified patient characteristics and health services patterns contributing to ED presentations. Methods We conducted a population‐based study of ED gout visits in Ontario, Canada, between 2014 and 2023.
Timothy S. H. Kwok   +7 more
wiley   +1 more source

Ice Dynamics and Morphological Changes During Proglacial Lake Development at Exploradores Glacier, Patagonia

open access: yesFrontiers in Earth Science, 2022
Proglacial lakes are ubiquitous features formed during deglaciarization and are currently increasing in number in Patagonia and elsewhere. Proglacial lakes can affect glacier dynamics, catchment hydrology and have the potential to cause glacial lake ...
Inigo Irarrazaval   +7 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

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