Results 121 to 130 of about 18,238 (212)

Electrostatic Self‐Assembly Induced Nest‐Like MXene Networks on Fabric for Ultra‐Broadband Flexible Absorption

Advanced Science, EarlyView.
In this study, an electrostatically self‐assembled WPU‐MXene@FC flexible fabric constructs a “nest‐like” structure on fibers, building construct MXene multiple loss paths, achieving ultra‐wideband absorption of 25.3–1200 GHz in a thickness of 1.8 mm, while also exhibiting superhydrophobicity, acid and alkali resistance, and bending resistance ...
Min Luo, Zihao Chen, Haotian Li, Kexun Li, Wei Wang, Weishi Jiao, Donghong Wang, Qiye Wen   +7 more
wiley   +1 more source

A study of the dynamics of the British Ice Sheet during Marine Isotope Stages 2 and 3, focusing on Heinrich Events 2 and 4 and their relationship to the North Atlantic glaciological and climatological conditions

, 2007
A high-resolution investigation into the stratigraphy of core MD95-2006 from the Barra fan, NW Scottish continental slope has been carried out. The study focuses on key palaeoceanographic proxies (percentage Neogloboquadrina pachyderma (s), planktonic ...
Leigh, Sasha Naomi Bharier
core  

High‐Performance Prevascularized SHED‐Laden rGO@Hydrogel Achieves Optimized Diabetic Bone Defect Repair

Advanced Science, EarlyView.
A high‐performance 3D scaffold integrating rGO and SHEDs is developed to overcome impaired healing in diabetic bone defects. By driving extracellular matrix remodeling, rGO creates a pro‐angiogenic niche that significantly accelerates in vitro vascular network formation.
Can Zhang, Yiyuan Kang, Shulin Lai, Chunyi Wang, Guixin He, Kehui Jian, Suhan Yin, Xiner Tan, Xinru Zhou, Wenjing Liu, Fujian Zhao, Jia Liu, Longquan Shao   +12 more
wiley   +1 more source

The deglaciation of the northwest sector of the last British-Irish ice sheet : integrating onshore and offshore data relating to chronology and behaviour

, 2013
It is now accepted that the last British-Irish Ice Sheet (BIIS) was highly dynamic and drained by numerous fast flowing ice streams. This dynamic nature combined with its maritime location made the BIIS sensitive to the rapid climate change that ...
Small, David
core  

Spatiotemporal Control of Formation of Dynamic Protein Fiber Assemblies via Photophysical Effects of a Focused Laser Beam

Advanced Science, EarlyView.
Tightly focused laser irradiation can accumulate tubulin proteins at/around the laser focus, which leads to the formation of highly ordered microtubule assemblies. The assemblies can exhibit various dynamic behaviors such as radial motion, bundling, and flagella‐like rotation with motor protein and chemical energy, highlighting as a unique tool for ...
Hiroshi Y. Yoshikawa, Ren Shirata, Takuya Takeshige, Riki Yoshida, Fumika Kiryu, Kei Takano, Shuma Matsumoto, Reiji Kawanami, Natsumi Sawada, Chi‐Shiun Wu, Yang‐Hsin Shih, Hiromasa Niinomi, Takahisa Matsuzaki, Seiichiro Nakabayashi, Tomoaki Matsuura, Teruki Sugiyama, Ryuzo Kawamura   +16 more
wiley   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Sensitivity of the Greenland Ice Sheet to Pliocene sea surface temperatures [PDF]

, 2010
The history of theGrIS (Greenland Ice Sheet), particularly in warm climates of the pre-Quaternary, is poorly known. IRD (ice-rafted debris) records suggest that the ice sheet has existed, at least transiently, since theMiocene and potentially since as ...
Haywood, Alan M., Hunter, Stephen J., Hill, Daniel J., Stoll, Danielle K., Dolan, Aisling M.   +4 more
core  

Molecular Engineering Mediated Interfacial Assembly as an Artificial Extracellular Matrix Remolds Bacteria With Enhanced Abiotic Resilience

Advanced Science, EarlyView.
A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang, Zili Jia, Yang Li, Qitao Wang, Shuai Hou, Lei Liu   +5 more
wiley   +1 more source