Results 101 to 110 of about 2,666,636 (245)

Reconstructing ice-sheet accumulation rates at ridge B, East Antarctica [PDF]

open access: yes, 2004
Understanding how ice sheets responded to past climate change is fundamental to forecasting how they will respond in the future. Numerical models calculating the evolution of ice sheets depend upon accumulation data, which are principally available from ...
Payne, Antony J   +11 more
core   +1 more source

Improvements on the discretisation of boundary conditions to the momentum balance for glacial ice

open access: yesJournal of Glaciology
The flow of glacial ice is typically approximated as a nonNewtonian viscous fluid, with the momentum balance described by (an approximation to) the Stokes equations, and the nonlinear rheology described by a flow law.
Constantijn J. Berends   +2 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

WAVI.jl: Ice Sheet Modelling in Julia [PDF]

open access: yes
Ice sheet models are used to improve our understanding of the past, present, and future evolution of ice sheets. To do so, they solve the equations describing the flow of ice when forced by other climate elements, particularly the atmosphere and oceans.
Williams, C. Rosie   +5 more
core   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung   +15 more
wiley   +1 more source

Quantifying subglacial roughness and its link to glacial geomorphology and ice speed [PDF]

open access: yes, 2013
The shape of subglacial bed topography, termed its roughness, is a recognised control on basal ice-flow. Although glaciologists have observed patterns of variations in ice speed over beds with different roughness values, the strength of this relationship
PRESCOTT, PHILIP,WILLIAM
core  

Water/Ionic Liquid Hybrid Electrolyte for High Cycling Stability and Low‐Temperature Adaptability in Aqueous Lithium‐Ion Battery

open access: yesAdvanced Science, EarlyView.
A dilute hybrid electrolyte containing only 10 mol% [EMIM][DEP] simultaneously reorganizes the water hydrogen‐bond network and creates an ionic‐liquid‐rich region at the anode. This coupled bulk and interfacial regulation suppresses freezing and hydrogen evolution, broadens the electrochemical stability window, and enables an aqueous LMO/LTP full cell ...
Jiwei He   +8 more
wiley   +1 more source

The deglaciation of the northwest sector of the last British-Irish ice sheet : integrating onshore and offshore data relating to chronology and behaviour [PDF]

open access: yes, 2013
It is now accepted that the last British-Irish Ice Sheet (BIIS) was highly dynamic and drained by numerous fast flowing ice streams. This dynamic nature combined with its maritime location made the BIIS sensitive to the rapid climate change that ...
Small, David
core   +2 more sources

How Greenland melts

open access: yesEPJ Web of Conferences, 2010
Satellite altimetry and gravimetry show that the Greenland ice sheet has been losing volume and mass since the beginning of this century. However, from these short time series of direct measurements we cannot infer what the causes of the mass loss are, i.
van den Broeke M.R.
doaj   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

open access: yesAdvanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang   +8 more
wiley   +1 more source

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