Results 81 to 90 of about 2,666,636 (245)

Testing hypotheses of the cause of peripheral thinning of the Greenland Ice Sheet: is land-terminating ice thinning at anomalously high rates? [PDF]

open access: yes, 2008
Recent observations have shown that the periphery of the Greenland ice sheet (GrIS) is thinning rapidly and that this thinning is greatest around marine-terminating outlet glaciers. Several theories have been proposed which provide a link between climate
Krabill, W   +14 more
core   +2 more sources

Modelling the diversion of erratic boulders by the Valais Glacier during the last glacial maximum

open access: yesJournal of Glaciology, 2017
In this study, a modelling approach was used to investigate the cause of the diversion of erratic boulders from Mont Blanc and southern Valais by the Valais Glacier to the Solothurn lobe during the Last Glacial Maximum (LGM). Using the Parallel Ice Sheet
GUILLAUME JOUVET   +3 more
doaj   +1 more source

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

open access: yesAdvanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching   +9 more
wiley   +1 more source

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

The evolution of the Greenland Ice Sheet from the Last Glacial Maximum to present-day: An assessment using glaciological and Glacial Isostatic Adjustment modelling [PDF]

open access: yes, 2009
In this thesis we constrain a three-dimensional thermomechanical model of Greenland ice sheet (GrIS) evolution from the Last Glacial Maximum (LGM, 21 ka BP) to the present-day using, primarily, observations of relative sea level (RSL) as well as field ...
SIMPSON, MATTHEW,JAMES,ROSS
core  

Relative importance of the mechanisms triggering the Eurasian ice sheet deglaciation in the GRISLI2.0 ice sheet model [PDF]

open access: yesClimate of the Past
The last deglaciation (21 to 8 ka) of the Eurasian ice sheet (EIS) is thought to have been responsible for a sea level rise of about 20 m. While many studies have examined the timing and rate of the EIS retreat during this period, many questions remain ...
V. van Aalderen   +3 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

open access: yesAdvanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait   +7 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Recent Advances in Carbon Cathode Materials toward High‐Performing Zinc‐Ion Hybrid Supercapacitors

open access: yesAdvanced Science, EarlyView.
Aqueous zinc‐ion hybrid supercapacitors (ZHSCs) have emerged as promising next‐generation electrochemical energy‐storage devices. Porous carbon materials have been extensively studied as cathodes, with advances in tailoring pore structures and material properties to enhance performance.
Take Hirooka   +3 more
wiley   +1 more source

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