Results 91 to 100 of about 4,612 (262)

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Emulator-based Bayesian calibration of a subglacial drainage model

Annals of Glaciology
Subglacial drainage models, often motivated by the relationship between hydrology and ice flow, sensitively depend on numerous unconstrained parameters.
Tim Hill, Gwenn E. Flowers, Derek Bingham, Matthew J. Hoffman   +3 more
doaj   +1 more source

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

Advanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida, Yanghao Zhong, Akiko Kumagai, William G. Dunphy, Shasha Chong   +4 more
wiley   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

An ice-sheet modelling framework to determine vulnerable regions of the Greenland Ice Sheet in the past [PDF]

The Cryosphere
The contribution of the Greenland Ice Sheet (GrIS) to sea-level rise is accelerating and there is an urgent need to characterize which sectors of the ice sheet are the most vulnerable. Estimating the volume of Greenland ice that was lost during past warm
B. A. Keisling, J. M. Schaefer, J. M. Schaefer, R. M. DeConto, J. P. Briner, N. E. Young, C. K. Walcott-George, C. K. Walcott-George, G. Winckler, G. Winckler, A. Balter-Kennedy, S. Anandakrishnan   +11 more
doaj   +1 more source

A backscattering and propagation model for radar sounding of ice sheets [PDF]

2016 IEEE International Geoscience and Remote Sensing Symposium (IGARSS), 2016
In this paper the electromagnetic properties of the continental ice sheets are modeled with the aim of assessing the feasibility of space-based radar ice sounding at P-band. The paper focuses on the model itself, as distinct from the estimation of model parameters and the exploitation of the model.
openaire   +2 more sources

N‐Doping Activated Presodiation Enhances Sodium‐Ion Provision in Hard Carbon Anodes

Advanced Science, EarlyView.
Introducing pyrrolic‐N sites enables efficient presodiation and stronger PF6− capture, thus pre ‐ forming a robust inorganic‐rich SEI layer in hard carbon anodes. ABSTRACT Hard carbon (HC) is considered the most promising anode material for commercial sodium‐ion batteries (SIBs), yet it still faces critical challenges such as low initial Coulombic ...
Hua Lin, Wenxing Miao, Yanrong Shi, Guangyi Mao, Ding Ding, Jian Weng, Zhongxiong Fan, Qingchi Xu, Jun Xu   +8 more
wiley   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

Advanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu, Huan Liu, Songyin Zhao, Lei Qin, Jiarui Li, Jun Wang, Zixuan Dai, Jie Gu, Yan Xu, Feiran Li, Yao Nie   +10 more
wiley   +1 more source

Improvements on the discretisation of boundary conditions to the momentum balance for glacial ice

Journal of Glaciology
The flow of glacial ice is typically approximated as a nonNewtonian viscous fluid, with the momentum balance described by (an approximation to) the Stokes equations, and the nonlinear rheology described by a flow law.
Constantijn J. Berends, Roderik S. W. van de Wal, Paul A. Zegeling   +2 more
doaj   +1 more source

Katabatic Winds on Ice Sheets: A Refinement of the Prandtl Model

Journal of the Atmospheric Sciences, 2007
Abstract Katabatic winds on ice sheets and glaciers are buoyancy-driven flows, much like turbidity currents in the ocean. These winds are driven by radiative cooling of the ice surface and are not resolved by the typical horizontal and vertical discretization of general circulation models; therefore, a parameterization of their magnitude
Zammett, R, Fowler, A
openaire   +3 more sources