Results 101 to 110 of about 3,902,696 (360)

A New Guitar Teaching Philosophy A New Guitar Teaching Philosophy

Acta Universitaria, 2012
In this present work it is given an opinion for a new approach to guitar teaching philosophy in a sufficiently sophisticated way, which surpasses up to now all known looks. With a goal to shed light on this important topic, this work will introduce a new
Ice B. Risteski
doaj  

Low-Cost Multifunctional Assistive Device for Visually Impaired Individuals

IEEE Access
Visually impaired individuals face challenges in mobility, object recognition, and text reading. Existing assistive tools provide partial solutions but lack full integration. This paper presents a low-cost, multifunctional assistive device in the form of
Richard Kral, Patrik Jacko, Tibor Vince
doaj   +1 more source

The Grounding of an Ice Shelf in the Central Arctic Ocean: A Modeling Experiment [PDF]

, 2003
A numerical ice sheet model was used in a first test towards evaluating the hypothesis that, during a period of large-scale glaciation, an ice shelf emanating from the Barents/Kara Seas grounded across parts of the Lomonosov Ridge to a depth of around ...
Jakobsson, Martin, Paton, Mark, Siegert, M   +2 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Can we learn from matter creation to solve the $$H_{0}$$ H 0 tension problem?

European Physical Journal C: Particles and Fields
The $$H_{0}$$ H 0 tension problem is studied in the light of a matter creation mechanism (an effective approach to replacing dark energy), the way to define the matter creation rate being of pure phenomenological nature.
Emilio Elizalde, Martiros Khurshudyan, Sergei D. Odintsov   +2 more
doaj   +1 more source

Overview of Ice Nucleating Particles

, 2017
Ice particle formation in tropospheric clouds significantly changes cloud radiative and microphysical properties. Ice nucleation in the troposphere via homogeneous freezing occurs at temperatures lower than −38°C and relative humidity with respect to ice
Z. Kanji, Luis A. Ladino, H. Wex, Y. Boose, Monika Burkert-Kohn, D. Cziczo, M. Krämer   +6 more
semanticscholar   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Application of Hollow Glass Microspheres in the Arctic Ocean Would Likely Lead to a Deceleration of Arctic Sea Ice Loss” ‐ A Critique of the Paper by Webster and Warren (2022)

Earth's Future
Avoiding the worst effects of global warming requires a multipronged approach including decarbonizing as quickly as possible, adaptation, greenhouse gas removal, and climate intervention.
A. Strawa, S. Olinger, S. Zornetzer, D. Johnson, S. Bhattacharyya, D. Ivanova, L. Field   +6 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A Novel Multidimensional Statistics Denoising Algorithm Based on Gaussian Mixture Model for Photon-Counting LiDAR Data

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The micropulse multibeam photon-counting laser altimeter significantly improves the sampling density along the orbit while introducing abundant noise.
Sitong Chen, Sheng Nie, Xiaohuan Xi, Shaobo Xia, Feng Zhu, Cheng Wang, Xiaoxiao Zhu   +6 more
doaj   +1 more source