Results 61 to 70 of about 70,688 (219)
Advanced Science, EarlyView.Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
Marginal ice zone fraction benchmarks sea ice and climate model skill. [PDF]
Nat Commun, 2021 Horvat C.
europepmc +1 more source
Advanced Science, EarlyView.FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni +17 more
wiley +1 more source
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Advanced Science, EarlyView.Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
Most long-lived contrails form within cirrus clouds with uncertain climate impact
Nature CommunicationsContrail-cirrus is considered the most important component of aviation-induced climate impact. However, a reliable assessment requires better understanding of their radiative effects.
Andreas Petzold +7 more
doaj +1 more source
System design options of decentralized autonomous renewable energy systems
Energy Conversion and Management: XGrowing climate related disruptions, geopolitical shocks, and increasing public interest in local energy security have intensified the motivation for municipalities to pursue energy autonomy as part of resilient and sustainable energy transitions ...
Lovindu Wijesinghe +5 more
doaj +1 more source
Advanced Science, EarlyView.Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley +1 more source
Impact of Market Reforms on Deterministic Frequency Deviations in the European Power Grid
IEEE Open Access Journal of Power and EnergyDeterministic frequency deviations (DFDs) are systematic and predictable excursions of grid frequency that arise from synchronized generation ramps induced by electricity market scheduling.
Philipp C. Bottcher +4 more
doaj +1 more source
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Investigating the economic dynamics of mobile money in Somalia's climate-stressed setting
Frontiers in ClimateThis study explores the role of mobile money in stimulating economic activities and enhancing economic resilience in Somalia's climate-stressed context.
Mohamed Ibrahim Nor +2 more
doaj +1 more source