Results 101 to 110 of about 737,718 (307)

18.0.A Daily Outline [PDF]

, 2016
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

5.0.C.1 Hands-on Gas Law Experiments [PDF]

, 2016
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Chris F.
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Global Distribution and Seasonality of Martian Atmospheric HCl Explained Through Heterogeneous Chemistry

Geophysical Research Letters
Recent observations from the ExoMars Trace Gas Orbiter (TGO) have revealed the presence of hydrogen chloride (HCl) in the martian atmosphere. HCl shows strong seasonality, primarily appearing during Mars' perihelion period before decreasing faster than ...
Paul M. Streeter, Kylash Rajendran, Stephen R. Lewis, Kevin S. Olsen, Alexander Trokhimovskiy, Oleg Korablev, Manish R. Patel   +6 more
doaj   +1 more source

Photochemistry of the PAH pyrene in water ice: the case for ion-mediated solid-state astrochemistry

, 2009
Context. Icy dust grains play an important role in the formation of complex inter- and circumstellar molecules. Observational studies show that polycyclic aromatic hydrocarbons (PAHs) are abundantly present in the ISM in the gas phase.
A. Bakker, Bernstein, Bernstein, Bito, Bouwman, Bouwman, Briggs, Draine, Draine, Draine, Fuchs, Gudipati, Gudipati, Gudipati, Gudipati, Gudipati, H. Linnartz, H. M. Cuppen, Halasinski, Hsiao, Ioppolo, J. Bouwman, Kjaergaard, Kobayashi, L. J. Allamandola, Langelaar, Li, Mathis, Milosavljevic, Montejano, Muñoz Caro, Okada, Okada, Shen, Smith, Sternberg, Stevens, Tielens, Vala, van Ijzendoorn, Wang, Weisman, Whittet, Woon, Öberg, Öberg, Öberg, Öberg, Öberg   +48 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Earth Observing System. Volume 1, Part 2: Science and Mission Requirements. Working Group Report Appendix [PDF]

Areas of global hydrologic cycles, global biogeochemical cycles geophysical processes are addressed including biological oceanography, inland aquatic resources, land biology, tropospheric chemistry, oceanic transport, polar glaciology, sea ice and ...

core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

16.0.D Materials Day 16 Convection Radiation [PDF]

, 2016
WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core   +1 more source