Results 81 to 90 of about 737,718 (307)
Tests of shock chemistry in IC 443G
The Astrophysical Journal, 1992 Eight molecular species, in the hot dense clump IC 443G, believed to be impacted by the shock wave from the SNR IC 443, are investigated. The clump consists of two distinct regions, one relatively cool, and one hotter and denser. Region 1 contains CO, HCO(+), HCN, and CN, whose abundances may be explained either by ion-molecule chemistry, or by a D ...
B. E. Turner +3 more
openaire +1 more source
Antarctic aerosol and snowfall chemistry: implications for deep Antarctic ice-core chemistry [PDF]
Annals of Glaciology, 1999 AbstractIn this paper we first summarise major findings of recent atmospheric studies of nitrogen and sulphur species present in the boundary layer of coastal Antarctic regions. We then discuss the implications of such atmospheric data for the interpretation of nitrate, ammonium, methanesulphonate and sulphate records in deep ice cores extracted from ...
Legrand, Michel +2 more
openaire +2 more sources
, 2020 WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
First-year sea-ice contact predicts bromine monoxide (BrO) levels at Barrow, Alaska better than potential frost flower contact [PDF]
Atmospheric Chemistry and Physics, 2007 Reactive halogens are responsible for boundary-layer ozone depletion and mercury deposition in Polar Regions during springtime. To investigate the source of reactive halogens in the air arriving at Barrow, Alaska, we measured BrO, an indicator of ...
W. R. Simpson +8 more
doaj
, 2020 WELCOME to WINDOWS on the INQUIRY CLASSROOM! You have landed on a piece of a National Science Foundation Project (DUE 1245730) directed by Professor Chris Bauer, Chemistry Department, University of New Hampshire.
Bauer, Christopher F.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The response of Antarctic sea ice algae to changes in pH and CO2.
PLoS ONE, 2014 Ocean acidification substantially alters ocean carbon chemistry and hence pH but the effects on sea ice formation and the CO2 concentration in the enclosed brine channels are unknown.
Andrew McMinn +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source