Results 41 to 50 of about 347,440 (309)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Average time scale for Dome Fuji ice core, East Antarctica

, 2004
P(論文)Three different approaches to ice-core age dating are employed to develop a depth-age relationship at Dome F: (1) correlation of the ice-core isotope record to the geophysical metronome(Milankovich surface temperature cycle) inferred from the deep ...
Shoji, Hitoshi, Lipenkov, Vladimir Ya., Salamatin, Andrey N., Hondoh, Takeo, Tsyganova, Elena A., Watanabe, Okitsugu   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Agile Sub-Ice Geological (ASIG) Drill development and Pirrit Hills field project

Annals of Glaciology, 2021
A new drilling system was developed by the US Ice Drilling Program (IDP) to rapidly drill through overlying ice to collect subglacial rock cores. The Agile Sub-Ice Geological (ASIG) Drill system is capable of drilling up to 700 m of ice in a continuous ...
Tanner Kuhl, Chris Gibson, Jay Johnson, Grant Boeckmann, Elliot Moravec, Kristina Slawny   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Evaluating marine dust records as templates for optical dating of Oldest Ice [PDF]

Climate of the Past
The continuous ice core record extends 800 000 years into the past, covering the period of 100 000-year glacial cycles but not the transition from 40 000-year glacial cycles (the mid-Pleistocene transition, 1.2–0.7 million years ago).
J. Ng, J. Severinghaus, R. Bay, D. Tosi
doaj   +1 more source

A full Stokes ice-flow model to assist the interpretation of millennial-scale ice cores at the high-Alpine drilling site Colle Gnifetti, Swiss/Italian Alps

Journal of Glaciology, 2020
The high-Alpine ice-core drilling site Colle Gnifetti (CG), Monte Rosa, Swiss/Italian Alps, provides climate records over the last millennium and beyond.
Carlo Licciulli, Pascal Bohleber, Josef Lier, Olivier Gagliardini, Martin Hoelzle, Olaf Eisen   +5 more
doaj   +1 more source

Ice-algal chlorophyll a and physical properties of multi-year and first-year sea ice of core CASIMBO-CORE-1_12

, 2015
Ice-algal chlorophyll a and physical properties of multi-year and first-year sea ice of core CASIMBO-CORE ...
Benjamin Allen Lange (6962450), Michel, Christine, Meisterhans, Guillaume, Ido Hatam (209666), Justin Beckers (6962453), Lange, Benjamin Allen, Haas, Christian, Niemi, Andrea, Hauke Flores (6979595), Hatam, Ido, Casey, J Alec, Andrea Niemi (8004593), Beckers, Justin, Christine Michel (8000204), Flores, Hauke, J Alec Casey (6962456), Christian Haas (6959543), Guillaume Meisterhans (728324)   +17 more
core   +1 more source

An assessment of key model parametric uncertainties in projections of Greenland Ice Sheet behavior [PDF]

, 2012
Lack of knowledge about the values of ice sheet model input parameters introduces substantial uncertainty into projections of Greenland Ice Sheet contributions to future sea level rise.
Stone, Emma J., N. Kirchner, K. Keller, Keller, K., Greve, Ralf, Applegate, P. J., Greve, R., R. Greve, Keller, Klaus, Kirchner, N., Applegate, Patrick J.,, Applegate, Patrick J., Kirchner, Nina, Stone, EJ, Kirchner, Nina,, E. J. Stone, Stone, E. J., P. J. Applegate   +17 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source