Results 51 to 60 of about 1,022,984 (305)

The Dominion Range Ice Core, Queen Maud Mountains, Antarctica - General Site and Core Characteristics with Implications [PDF]

open access: yes, 2017
The Transantarctic Mountains of East Antarctica provide a new milieu for retrieval of ice-core records. We report here on the initial findings from the first of these records, the Dominion Range ice-core record.
Gow, Anthony J.   +9 more
core   +1 more source

Separating gas-giant and ice-giant planets by halting pebble accretion [PDF]

open access: yes, 2014
In the Solar System giant planets come in two flavours: 'gas giants' (Jupiter and Saturn) with massive gas envelopes and 'ice giants' (Uranus and Neptune) with much thinner envelopes around their cores.
Johansen, Anders   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Potential to recover a record of Holocene climate and sea ice from Müller Ice Cap, Canada

open access: yesJournal of Glaciology
Müller Ice Cap sits on Umingmat Nunaat (Axel Heiberg Island), Nunavut, Canada, ~ 80°N. Its high latitude and elevation suggest it experiences relatively little melt and preserves an undisturbed paleoclimate record.
David Armond Lilien   +12 more
doaj   +1 more source

Temporal and spatial variability of snow accumulation in central Greenland [PDF]

open access: yes, 1997
Snow accumulation records from central Greenland are explored to improve the understanding of the accumulation signal in Greenland ice core records. Results from a “forest” of 100 bamboo poles and automated accumulation monitors in the vicinity of Summit
Bolzan   +15 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Inferring geothermal heat flux from an ice-borehole temperature profile at Law Dome, East Antarctica

open access: yesJournal of Glaciology, 2020
Geothermal heat flux (GHF) is an important control on the dynamics of Antarctica's ice sheet because it controls basal melt and internal deformation. However, it is hard to estimate because of a lack of in-situ measurements.
Laura Mony   +2 more
doaj   +1 more source

Age ranges of the Tibetan ice cores with emphasis on the Chongce ice cores, western Kunlun Mountains [PDF]

open access: yesThe Cryosphere, 2018
An accurate chronology is the essential first step for a sound understanding of ice core records. However, dating ice cores drilled from the high-elevation glaciers is challenging and often problematic, leading to great uncertainties.
S. Hou   +10 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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