Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Potential to recover a record of Holocene climate and sea ice from Müller Ice Cap, Canada
Journal of GlaciologyMüller Ice Cap sits on Umingmat Nunaat (Axel Heiberg Island), Nunavut, Canada, ~ 80°N. Its high latitude and elevation suggest it experiences relatively little melt and preserves an undisturbed paleoclimate record.
David Armond Lilien +12 more
doaj +1 more source
Inferring geothermal heat flux from an ice-borehole temperature profile at Law Dome, East Antarctica
Journal of Glaciology, 2020 Geothermal heat flux (GHF) is an important control on the dynamics of Antarctica's ice sheet because it controls basal melt and internal deformation. However, it is hard to estimate because of a lack of in-situ measurements.
Laura Mony +2 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Reconstruction of past atmospheric CO2 concentrations by ice core analyses [PDF]
, 2000 International Symposium on Physics of Ice Core Records.
Stauffer, Bernhard +2 more
core +1 more source
Evaluating marine dust records as templates for optical dating of Oldest Ice [PDF]
Climate of the PastThe continuous ice core record extends 800 000 years into the past, covering the period of 100 000-year glacial cycles but not the transition from 40 000-year glacial cycles (the mid-Pleistocene transition, 1.2–0.7 million years ago).
J. Ng, J. Severinghaus, R. Bay, D. Tosi
doaj +1 more source
Physical properties of the Dome Fuji deep ice core (review) [PDF]
, 2003 P(論文)Recent results of physical analyses of the Dome Fuji ice core are summarized with special attention to new methods introduced in the present studies.
Fukumura, Taku +19 more
core
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Age ranges of the Tibetan ice cores with emphasis on the Chongce ice cores, western Kunlun Mountains [PDF]
The Cryosphere, 2018 An accurate chronology is the essential first step for a sound understanding of ice core records. However, dating ice cores drilled from the high-elevation glaciers is challenging and often problematic, leading to great uncertainties.
S. Hou +10 more
doaj +1 more source
record between 40 and 8 kyr B.P. from the Greenland Ice Core Project ice core [PDF]
, 1997 CO2 ice-core records show an increase in the atmospheric concentration of 80–100 parts per million by volume (ppmv) from the last glacial maximum (LGM) to the early Holocene.
J. M. Barnola +13 more
core +1 more source