Results 71 to 80 of about 1,022,984 (305)

Implementation of counted layers for coherent ice core chronology [PDF]

Climate of the Past, 2015
A recent coherent chronology has been built for four Antarctic ice cores and the NorthGRIP (NGRIP) Greenland ice core (Antarctic Ice Core Chronology 2012, AICC2012) using a Bayesian approach for ice core dating (Datice).
B. Lemieux-Dudon, L. Bazin, A. Landais, H. Toyé Mahamadou Kele, M. Guillevic, P. Kindler, F. Parrenin, P. Martinerie   +7 more
doaj   +1 more source

Atmospheric neutrino oscillations and tau neutrinos in ice [PDF]

, 2010
The main goal of the IceCube Deep Core Array is to search for neutrinos of astrophysical origins. Atmospheric neutrinos are commonly considered as a background for these searches. We show here that cascade measurements in the Ice Cube Deep Core Array can
Gerardo Giordano, Irina Mocioiu, O. Schulz, Olga Mena   +3 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Anthropogenic signals recorded in an ice core from Eclipse Icefield, Yukon Territory, Canada [PDF]

, 2001
Trends in the annual flux of sulfate and nitrate in a new ice core collected at an elevation of 3017 m on Eclipse Icefield, 45 km northeast of Mt. Logan were examined to determine the effect of anthropogenic activity on precipitation chemistry in the ...
Wake, Cameron P, Yalcin, Kaplan
core   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Isotopic variations of meltwater from ice by isotopic exchange between liquid water and ice

Journal of Glaciology, 2019
Predicting the isotopic modification of ice by melting processes is important for improving the accuracy in paleoclimate reconstruction. To this end, we present results from cold room laboratory observations of changes in the isotopic ratio (D/H and 18O ...
Ji-Young Ham, Soon Do Hur, Won Sang Lee, Yeongcheol Han, Hyejung Jung, Jeonghoon Lee   +5 more
doaj   +1 more source

Surface accumulation in Northern Central Greenland during the last 300 years

Annals of Glaciology, 2020
The internal stratigraphy of snow and ice as imaged by ground-penetrating radar may serve as a source of information on past accumulation. This study presents results from two ground-based radar surveys conducted in Greenland in 2007 and 2015 ...
Nanna B. Karlsson, Sebastian Razik, Maria Hörhold, Anna Winter, Daniel Steinhage, Tobias Binder, Olaf Eisen   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Core handling and processing for the WAIS Divide ice-core project [PDF]

, 2014
On 1 December 2011 the West Antarctic Ice Sheet (WAIS) Divide ice-core project reached its final depth of 3405 m. The WAIS Divide ice core is not only the longest US ice core to date, but is also the highest-quality deep ice core, including ice from the ...
Bencivengo, Brian M, Cravens, Eric D, Hargreaves, Geoffrey M, Johnson, Jay A, Kippenhan, Matthew J, Neff, Peter D, Nunn, Richard M, Orsi, Anais J, Popp, Trevor J, Rhoades, John F, Souney, Joseph, Jr, Taylor, Kendrick C, Twickler, Mark S, Vaughn, Bruce H, Voigt, Donald E, Wong, Gifford J   +15 more
core   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source