Results 241 to 250 of about 161,313 (308)

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

A possible volcanic origin for the Greenland ice core Pt anomaly near the Bølling-Allerød/Younger Dryas boundary. [PDF]

PLoS One
Green CE, Baldini JUL, Brown RJ, Schmincke HU, Edmonds M, Meisel TC.   +5 more
europepmc   +1 more source

Distinct bacterial community structures with abundant carbon degradation and sulfur metabolisms found in different sea-ice types from the Central Arctic Ocean. [PDF]

Microbiol Spectr
Venkatachalam S, Granskog MA, Gonçalves-Araujo R, Divine DV, Vipindas PV, Jabir T, Shereef A, Jain A.   +7 more
europepmc   +1 more source

Volcanism-induced collapse and recovery of the Atlantic meridional overturning circulation under glacial conditions. [PDF]

Sci Adv
Vettoretti G, Hu RJ, Bethke I, Krüger K, Sigl M, Outten S, Lin J, Nuterman R, Svensson A, Ditlevsen P, Jochum M.   +10 more
europepmc   +1 more source

A review of microplastic contamination in the cryosphere. [PDF]

iScience
Qayoom I, Jan FZ, Rashid I, Bhat GA, Ambili A, Sarangi C.   +5 more
europepmc   +1 more source

Amplicon sequencing of ice and water phytoplankton and bacterial communities during an extreme winter in a central Canadian great lake. [PDF]

Microbiol Resour Announc
Rozmarynowycz MJ, Brown KM, Gantz JD, Lee RE, Zastepa A, Watson S, McKay RML.   +6 more
europepmc   +1 more source

A radiometric timescale challenges the chronology of the iconic 1992 Guliya ice core. [PDF]

Sci Adv
Hou S, Jenk TM, Jiang W, Zhang W, Hu H, Feng X, Li H, Wu SY, Pang H, Yu J, Huang R, Lu ZT, Yang GM, Bender M, Schwikowski M.   +14 more
europepmc   +1 more source

Reconstructing East Antarctic Temperature and Snowfall Variability from δ15N of N2

Bouchet M, Landais A, Klüssendorf AM, Brückner L, Legrain E, Capron E, Parrenin F, Menviel L, Grisart A, Prié F, Extier T, Jacob R, Fischer H, Traeger H, Tinner P, Schmitt J, Grimmer M.   +16 more
europepmc   +1 more source

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ICE CORES

2014
Ice cores from Antarctica, from Greenland, and from a number of smaller glaciers around the world yield a wealth of information on past climates and environments. Ice cores offer unique records on past temperatures, atmospheric composition (including greenhouse gases), volcanism, solar activity, dustiness, and biomass burning, among others.
openaire   +3 more sources