Results 111 to 120 of about 24,268 (294)

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

The Second Deep Ice Coring at Dome Fuji, Antarctica.

Antarctic Record, 2020
The second deep ice coring project was carried out at Dome Fuji, Antarctica. Following the pilot hole drilling in 2001, deep ice core drilling was conducted for four years from the 2003/2004 austral summer season, reaching a depth of 3035.22 m in January
Hideaki Motoyama, Akiyoshi Takahashi, Yoichi Tanaka, Kunio Shinbori, Morihiro Miyahara, Takayasu Yoshimoto, Yoshiyuki Fujii, Toshitaka Suzuki, Teruo Furukawa, Kumiko Goto-Azuma, Keisuke Suzuki, Atsuhiro Muto, Makoto Igarashi, Tetsuhide Yamasaki, Shuji Fujta, Takeshi Saito, Genta Watanabe, Atsushi Furusaki, Yuanscheng Li, Chung Ji Woong, Kotaro Fukui, Fumio Nakazawa, Takao Kameda, Koji Fujita, Ichio Obinata, Takashi Saito, Kokichi Kamiyama, Jun Kinoshita, Nobuhiko Azuma, Yoshiki Nakayama, Okitsugu Watanabe, Morimasa Takata, Yukio Ozawa, Akio Kobayashi, Yasushi Yoshise   +34 more
doaj   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Report on lake/marine sediment coring from ice surface (JARE-58/59)

Antarctic Record, 2018
Lake and marine sediment coring were carried out in the Soya Coast in East Antarctica, during the 2017⊖2018 summer season as part of the 58/59th Japanese Antarctic Research Expedition (JARE).
Yusuke Suganuma, Yukiko Tanabe, Kota Katsuki, Daisuke Shibata, Moto Kawamata   +4 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Programmable DNA‐Peptide Hybrid Nanostructures for Potent Neutralization of Multiple Influenza a Virus Subtypes

Advanced Functional Materials, EarlyView.
A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao, Abhisek Dwivedy, Payton L. Haak, Dhanush Gandavadi, Laurie A. Rund, Chi Chen, Vineetha Mareddy, Lifeng Zhou, Jinwei Duan, Ying Fang, Andrew J. Steelman, Xing Wang   +11 more
wiley   +1 more source

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Fully Bio‐Based Gelatin Organohydrogels via Enzymatic Crosslinking for Sustainable Soft Strain and Temperature Sensing

Advanced Functional Materials, EarlyView.
Enzymatically crosslinked gelatin‐based organohydrogels, fabricated through a fully bio‐based and scalable process, exhibit exceptional strain and temperature sensing capabilities with minimal interference from environmental humidity. These transparent, stretchable, and ionically conductive materials operate without synthetic fillers or dopants.
Pietro Tordi, Adrián Tamayo, Yeonsu Jeong, Bin Han, Tamer Al Kayal, Aida Cavallo, Massimo Bonini, Paolo Samorì   +7 more
wiley   +1 more source

5. Wochenbericht MSM01/3 [PDF]

, 2006
Maria S. Merian Cruise 1 leg 3 Last report: 10. 05. - 18. 05. 2006 Der 3. Fahrtabschnitt der 1. Reise des neuesten deutschen Forschungsschiffes Maria S. Merian führt in die Schlammvulkanprovinz des Golf von Cadiz.
Pfannkuche, Olaf
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