Results 41 to 50 of about 24,268 (294)

Antarctic subglacial drilling rig: Part II. Ice and Bedrock Electromechanical Drill (IBED)

open access: yesAnnals of Glaciology, 2021
A new, modified version of the cable-suspended Ice and Bedrock Electromechanical Drill (IBED) was designed for drilling in firn, ice, debris-rich ice and rock.
Pavel Talalay   +18 more
doaj   +1 more source

Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study). [PDF]

open access: yes, 2013
BackgroundTransseptal puncture is a critical step in achieving left atrial (LA) access for a variety of cardiac procedures. Although the mechanical Brockenbrough needle has historically been used for this procedure, a needle employing radiofrequency (RF)
Badhwar, Nitish   +13 more
core   +1 more source

New Seismic Methods to Support Sea-Ice Platform Drilling [PDF]

open access: yesScientific Drilling, 2009
The ANtarctic geological DRILLing Program (ANDRILL)is currently a consortium of five nations (Germany, Italy, New Zealand, the United Kingdom, a and the United States of America).
Stephen F. Pekar   +4 more
doaj   +1 more source

Viability of chemical and water isotope ratio measurements of RAID ice chippings from Antarctica

open access: yesJournal of Glaciology, 2023
The British Antarctic Survey's (BAS) Rapid Access Isotope Drill (RAID), designed for rapid drilling to survey prospective ice core sites, has been deployed at multiple Antarctic locations over 6 years.
Isobel F. Rowell   +4 more
doaj   +1 more source

Air reverse circulation at the hole bottom in ice-core drilling

open access: yesJournal of Glaciology, 2019
Ice-core drilling to depths of 200–300 m is an important part of research studies concerned with paleoclimate reconstruction and anthropogenic climate change. However, conventional drilling methods face difficulties due to firn permeability.
ZHENGYI HU   +7 more
doaj   +1 more source

Antarctic subglacial drilling rig: Part I. General concept and drilling shelter structure

open access: yesAnnals of Glaciology, 2021
Drilling to the bedrock of ice sheets and glaciers offers unique opportunities for examining the processes occurring in the bed. Basal and subglacial materials contain important paleoclimatic and paleoenvironmental records and provide a unique habitat ...
Pavel Talalay   +13 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Expedition 306 summary

open access: yes, 2006
The overall aim of the North Atlantic paleoceanography study of Integrated Ocean Drilling Program Expedition 306 is to place late Neogene–Quaternary climate proxies in the North Atlantic into a chronology based on a combination of geomagnetic ...
Aboud, Essam   +26 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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