Results 51 to 60 of about 24,371 (312)

Core handling and processing for the WAIS Divide ice-core project [PDF]

, 2017
On 1 December 2011 the West Antarctic Ice Sheet (WAIS) Divide ice-core project reached its final depth of 3405 m. The WAIS Divide ice core is not only the longest US ice core to date, but is also the highest-quality deep ice core, including ice from the ...
Bencivengo, Brian M., Cravens, Eric D., Hargreaves, Geoffrey M., Johnson, Jay A., Kippenhan, Matthew J., Neff, Peter D., Nunn, Richard M., Orsi, Anais J., Popp, Trevor J., Rhoades, John F., Souney, Joseph M., Taylor, Kendrick C., Twickler, Mark S., Vaughn, Bruce H., Voigt, Donald E., Wong, Gifford J.   +15 more
core   +1 more source

PANGAEA information system for glaciological data management [PDF]

, 1998
Specific parameters determined on cores from continental ice sheets or glaciers can be used to reconstruct former climate. To use this scientific resource effectively an information system is needed which guarantees consistent longtime storage of data ...
Diepenbroek, Michael, Fütterer, Dieter, Grobe, Hannes, Miller, Heinrich, Reinke, Manfred, Sieger, Rainer   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Core handling, transportation and processing for the South Pole ice core (SPICEcore) project

Annals of Glaciology, 2021
An intermediate-depth (1751 m) ice core was drilled at the South Pole between 2014 and 2016 using the newly designed US Intermediate Depth Drill. The South Pole ice core is the highest-resolution interior East Antarctic ice core record that extends into ...
Joseph M. Souney, Mark S. Twickler, Murat Aydin, Eric J. Steig, T. J. Fudge, Leah V. Street, Melinda R. Nicewonger, Emma C. Kahle, Jay A. Johnson, Tanner W. Kuhl, Kimberly A. Casey, John M. Fegyveresi, Richard M. Nunn, Geoffrey M. Hargreaves   +13 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A laboratory investigation of ice cutting with a lightweigt electromechanical drill

Antarctic Record, 1988
A lightweight mechanical ice core drill of shallow depth capability was tested in a cold laboratory to obtain basic chracteristics of electromechanical drills in connection with a development of a deep ice core drilling system.
Yoshiyuki Fujii, Yoichi Tanaka, Hideki Narita, Moriatsu Miyahara, Akiyoshi Takahashi   +4 more
doaj   +1 more source

SOAR (Support Office for Aerogeophysical Research) Annual Report 1994/1995 [PDF]

, 1995
The Support Office for Aerogeophysical Research (SOAR) was a facility of the National Science Foundation's Office of Polar Programs whose mission is to make airborne geophysical observations available to the broad research community of geology ...
Bell, Robin E., Blankenship, Donald D., Najmulski, Keith A.   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Mineral dust variability in central West Antarctica associated with ozone depletion [PDF]

Atmospheric Chemistry and Physics, 2013
We present here data of mineral dust variability retrieved from an ice core of the central West Antarctic, spanning the last five decades. Main evidence provided by the geochemical analysis is that northerly air mass incursions to the coring site ...
M. Cataldo, H. Evangelista, J. C. Simões, R. H. M. Godoi, I. Simmonds, M. H. Hollanda, I. Wainer, F. Aquino, R. Van Grieken   +8 more
doaj   +1 more source