Results 61 to 70 of about 3,234 (297)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Microstructure evolution of young sea ice from a Svalbard fjord using micro-CT analysis

Journal of Glaciology, 2022
We analysed the three-dimensional microstructure of sea ice by means of X-ray-micro computed tomography. Microscopic (brine- and air- pore sizes, numbers and connectivity) and macroscopic (salinity, density, porosity) properties of young Arctic sea ice ...
Martina Lan Salomon, Sönke Maus, Chris Petrich   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Overview Maps of the study region and ice coring sites.

, 2015
a) Map of the Arctic Ocean with an outline of the study region. b) Map of the Lincoln Sea and neighboring regions. Drifting ice sites (pack ice), ocean bathymetry, and an outline of landfast ice sites are indicated.
Hauke Flores (181232), Justin F. Beckers (728322), J. Alec Casey (728323), Ido Hatam (209666), Andrea Niemi (669403), Christine Michel (669404), Christian Haas (3185721), Benjamin A. Lange (728321), Guillaume Meisterhans (728324)   +8 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Expedition 302 geophysics: integrating past data with new results

, 2006
In preparation for IODP Expedition 302, Arctic Coring Expedition (ACEX), a site survey database comprising geophysical and geological data from the Lomonosov Ridge was compiled.
Kaminski, M., Backman, J., Martinez, N.C., Pälike, H., Smith, D.C., Jakobsson, M., Rio, D., Matthiessen, J., Rea, B., O'Regan, M., Moore, T.C., King, J., Onodera, J., Brinkhuis, H.K., Takahashi, K., Sakamoto, T., Watanabe, M., Koç, N., Rea, B.R., Dickens, G.R., Clemens, S., T. Floden, Stein, R., Brinkhuis, H., M. Jakobsson, Suto, I., Eynaud, F., Gattacceca, J., Flodén, T., Cronin, T., St. John, K.E.K., Moran, K., Moore Jr., T.C., Yamamoto, M., Jordan, R.W., McInroy, D., Suzuki, N.   +36 more
core   +1 more source

A laboratory investigation of ice cutting with a lightweigt electromechanical drill

Antarctic Record, 1988
A lightweight mechanical ice core drill of shallow depth capability was tested in a cold laboratory to obtain basic chracteristics of electromechanical drills in connection with a development of a deep ice core drilling system.
Yoshiyuki Fujii, Yoichi Tanaka, Hideki Narita, Moriatsu Miyahara, Akiyoshi Takahashi   +4 more
doaj   +1 more source

Core handling, transportation and processing for the South Pole ice core (SPICEcore) project

Annals of Glaciology, 2021
An intermediate-depth (1751 m) ice core was drilled at the South Pole between 2014 and 2016 using the newly designed US Intermediate Depth Drill. The South Pole ice core is the highest-resolution interior East Antarctic ice core record that extends into ...
Joseph M. Souney, Mark S. Twickler, Murat Aydin, Eric J. Steig, T. J. Fudge, Leah V. Street, Melinda R. Nicewonger, Emma C. Kahle, Jay A. Johnson, Tanner W. Kuhl, Kimberly A. Casey, John M. Fegyveresi, Richard M. Nunn, Geoffrey M. Hargreaves   +13 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source