Results 61 to 70 of about 562,841 (289)

Inland activities of the 43rd Japanese Antarctic Research Expedition related to deep ice coring project at Dome Fuji Station, Antarctica, II, 2002-2003

open access: yesAntarctic Record, 2005
Inland activities of wintering party of the 43rd Japanese Antarctic Research Expedition (JARE-43) related to the deep ice coring project at Dome Fuji, Antarctica, II were reported.
Takashi Saito, Jun Kinoshita
doaj   +1 more source

Antarctic subglacial drilling rig: Part I. General concept and drilling shelter structure

open access: yesAnnals of Glaciology, 2021
Drilling to the bedrock of ice sheets and glaciers offers unique opportunities for examining the processes occurring in the bed. Basal and subglacial materials contain important paleoclimatic and paleoenvironmental records and provide a unique habitat ...
Pavel Talalay   +13 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

The Pico Lightweight Coring Auger

open access: yes, 1984
A new lightweight hand-operated coring auger for use in firn or ice is described. Extensive use of glass-epoxy composites contributes to a drill weight of approximately 1 kg/m in 20 m and 50 m configurations.
Bruce R. Koci, Karl C. Kuivinen
core   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

RELATIONSHIP BETWEEN WEAK ENTWINING STRUCTURES AND WEAK CORINGS [PDF]

open access: yes, 2010
Given a commutative ring with unit, -algebra and -coalgebra Triple is called (weak) entwining structure if there is -linear map that fulfil some axioms.
Puspita, Nikken Prima
core   +1 more source

Spatial and temporal variability in the snowpack of a High Arctic ice cap: implications for mass-change measurements [PDF]

open access: yes, 2008
Interpretation of ice mass elevation changes observed by satellite altimetry demands quantification of the proportion of elevation change which is attributable to variations in firn densification.
Bell, Christina   +16 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

A laboratory investigation of ice cutting with a lightweigt electromechanical drill

open access: yesAntarctic Record, 1988
A lightweight mechanical ice core drill of shallow depth capability was tested in a cold laboratory to obtain basic chracteristics of electromechanical drills in connection with a development of a deep ice core drilling system.
Yoshiyuki Fujii   +4 more
doaj   +1 more source

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