Recent atmospheric Pb deposition at a rural site in southern Germany assessed using a peat core and snowpack, and comparison with other archives [PDF]
, 2005 In a peat bog from Black Forest, Southern Germany, the rate of atmospheric Pb accumulation was quantified using a peat core dated by 210Pb and 14C. The most recent Pb accumulation rate (2.5 mg m−2 y−1) is similar to that obtained from a snowpack on the ...
Aubert, Dominique +7 more
core +3 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Glacier clear ice bands indicate englacial channel microbial distribution
Journal of Glaciology, 2021 Distant glacial areas are interconnected by a complex system of fractures and water channels which run in the glacier interior and characterize the englacial realm.
Gilda Varliero +5 more
doaj +1 more source
Coastal permafrost landscape development since the Late Pleistocene in the western Laptev Sea, Siberia [PDF]
, 2011 The palaeoenvironmental development of the western Laptev Sea is understood primarily from investigations of exposed cliffs and surface sediment cores from the shelf.
Andreev, Andrei +6 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Internal structure and origin of the double reefs of North Bohol and the Olango reef flat (Philippines) [PDF]
, 1985 Nine holes were drilled with a submersible hydraulic drill into the slopes and reef flats of the Caubyna and Calituban reefs as well as of Olango Flat. The maximum depth of core penetration was 11 m.
Grobe, Hannes +2 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Characteristics of ice rises and ice rumples in Dronning Maud Land and Enderby Land, Antarctica
Journal of Glaciology, 2020 Ice rises and rumples, locally grounded features adjacent to ice shelves, are relatively small yet play significant roles in Antarctic ice dynamics. Their roles generally depend upon their location within the ice shelf and the stage of the ice-sheet ...
Vikram Goel +5 more
doaj +1 more source
Wind control on the accumulation of heavy metals in sediment of Lake Ulubat, Anatolia, Turkey [PDF]
, 2009 Freshwater Lake Ulubat (zmean = 1.5-2.0 m and Area = ~138 km2), NW Anatolia, Turkey was filled in by fine-to-medium-grain silts during the late Holocene.
Costa, PJM +8 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source