Results 61 to 70 of about 481,486 (293)

Ice coring and drilling technologies developed by the Polar Ice Coring Office [PDF]

open access: yes, 1994
P(論文)The search for "zero defects" ice cores continues to challenge the ice coring and drilling community. No single drilling and coring device will fill all needs.
Stanford,K.   +4 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

State of the art: review of coring and core analysis technology

open access: yes, 2000
The main goal of core analysis is to reduce uncertainty in reservoir evaluation by providing data representative of the reservoir at in- situ conditions. Basic core analysis measurements are unchanged, but advances in core analysis techniques provide the
M.A. Al-Saddique   +5 more
core   +1 more source

Hot-water coring system with positive displacement motor

open access: yes, 2020
In this study, a new coring system is designed that uses a positive displacement motor (PDM) connected to a core barrel and drill bit in combination with a hot-water drilling (HWD) system. The surface equipment and water hose are shared and the hot-water
Liu, An   +6 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Cover ICE 2019

open access: yes, 2019
These proceedings are a collection of papers presented in English at The Second PGSD UST International Conference on Education (ICE) held in Universitas Sarjanawiyata Tamansiswa on October 5, 2019.
ICE 2019, ICE 2019
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

RELATIONSHIP BETWEEN WEAK ENTWINING STRUCTURES AND WEAK CORINGS [PDF]

open access: yes, 2010
Given a commutative ring with unit, -algebra and -coalgebra Triple is called (weak) entwining structure if there is -linear map that fulfil some axioms.
Puspita, Nikken Prima
core   +1 more source

Characteristics of ice rises and ice rumples in Dronning Maud Land and Enderby Land, Antarctica

open access: yesJournal of Glaciology, 2020
Ice rises and rumples, locally grounded features adjacent to ice shelves, are relatively small yet play significant roles in Antarctic ice dynamics. Their roles generally depend upon their location within the ice shelf and the stage of the ice-sheet ...
Vikram Goel   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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