Results 71 to 80 of about 3,090,231 (345)

Assessing ice-cliff backwasting and its contribution to total ablation of debris-covered Miage glacier, Mont Blanc massif, Italy [PDF]

, 2014
Continuous surface debris cover strongly reduces the ablation of glaciers, but high melt rates may occur at ice cliffs that are too steep to hold debris.
Brock, B.w., Reid, Tim, Brock, Benjamin
core   +1 more source

The Changing Arctic Sea Ice Cover [PDF]

Oceanography, 2011
Arctic sea ice cover has declined over the past few decades. The end of summer September ice extent reached a record minimum in 2007. While there has been a modest recovery since then, the past four years (2007–2010) show the lowest sea ice extent in the
Donald K. Perovich
doaj  

Modeling present and future ice covers in two Antarctic lakes

Journal of Glaciology, 2020
Antarctic lakes with perennial ice covers provide the opportunity to investigate in-lake processes without direct atmospheric interaction, and to study their ice-cover sensitivity to climate conditions.
Sebastián Echeverría, Mark B. Hausner, Nicolás Bambach, Sebastián Vicuña, Francisco Suárez   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Representing moisture fluxes and phase changes in glacier debris cover using a reservoir approach

, 2014
Due to the complexity of treating moisture in supraglacial debris, surface energy balance models to date have neglected moisture infiltration and phase changes in the debris layer.
Essery, Richard, Bush, A. B.G., A. B. G. Bush, Maussion, F., Brock, B. W., Nicholson, Lindsey, Bush, Andrew, L. I. Nicholson, Collier, Emily, F. Maussion, Maussion, Fabien, Collier, E., Nicholson, L. I., R. Essery, Brock, Benjamin, Essery, R., E. Collier, B. W. Brock   +17 more
core   +1 more source

Spatial and temporal variability in the snowpack of a High Arctic ice cap: implications for mass-change measurements [PDF]

, 2008
Interpretation of ice mass elevation changes observed by satellite altimetry demands quantification of the proportion of elevation change which is attributable to variations in firn densification.
Bell, Christina, Burgess, David, Mair, Douglas, Demuth, Michael, Sharp, Martin, Demuth M, Bell C, Wadham J, Bingham, Robert, Mair D, Bingham R, Jacka J, Cawkwell, Fiona, Wadham, Jemma, Cawkwell F, Burgess D, Sharp M   +16 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Improving the spatial distribution of modeled Arctic sea ice thickness

, 2005
The spatial distribution of ice thickness/draft in the Arctic Ocean is examined using a sea ice model. A comparison of model predictions with submarine observations of sea ice draft made during cruises between 1987 and 1997 reveals that the model has the
Laxon, SW, Miller, PA, Feltham, DL, Laxon, S. W., Feltham, D. L., Miller, P. A.   +5 more
core   +1 more source

Modeling inter-annual and spatial variability of ice cover in a temperate lake with complex morphology

, 2020
The formation of ice cover on lakes alters heat and energy transfer with the water column. The fraction of surface area covered by ice and the timing of ice‐on and ice‐off therefore affects hydrodynamics and the seasonal development of stratification and
David Hamilton, Hofmann, Hilmar, Irene Caramatti, Peeters, Frank, Frank Peeters, Caramatti, Irene, Hilmar Hofmann, Hamilton, David, Hamilton, David P.   +8 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source