Results 41 to 50 of about 183,990 (318)
Timing of the Recent Migration and Intensification of the Southern Hemisphere Westerly Winds
Geophysical Research LettersIn recent decades, the Southern Hemisphere westerly winds have strengthened and migrated south, attributed to greenhouse gas emissions and stratospheric ozone depletion. However, the onset and acceleration of these drivers is coincident with the start of
Dieter R. Tetzner +4 more
doaj +1 more source
Dynamical Instabilities of Ice X
Physical Review Letters, 2008 Water ice X is stable in the 120-400 GPa pressure range, as obtained from lattice dynamical calculations performed using the density-functional theory. Below 120 GPa, it is characterized by one unstable flat phonon band, which generates the disordered ice X structure.
openaire +3 more sources
Dynamic behaviour of rutford ice stream [PDF]
Annals of Glaciology, 1982 The grounding-line region of Rutford Ice Stream was surveyed from the ground during 1978–79 and 1979–80, and from the air in 1980–81. Maps of surface elevation and ice thickness of an area of 1 000 km2allow the grounding line to be delineated and show that the ice stream consists of several distinct fingers of thick ice trending parallel to the flow ...
Stephenson, S.N, Doake, C.S.M
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Detecting dynamics of cave floor ice with selective cloud-to-cloud approach [PDF]
The Cryosphere, 2019 Ice caves can be considered an indicator of the long-term changes in the landscape. Ice volume is dynamic in the caves throughout the year, but the inter-seasonal comparison of ice dynamics might indicate change in the hydrological–climatic regime of ...
J. Šupinský +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Dynamics of colloidal particles in ice [PDF]
The Journal of Chemical Physics, 2011 We use x-ray photon correlation spectroscopy (XPCS) to probe the dynamics of colloidal particles in polycrystalline ice. During freezing, the dendritic ice morphology and rejection of particles from the ice created regions of high particle density, where some of the colloids were forced into contact and formed disordered aggregates.
Spannuth, Melissa +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source