Results 61 to 70 of about 3,816,888 (295)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Detecting dynamics of cave floor ice with selective cloud-to-cloud approach [PDF]

open access: yesThe Cryosphere, 2019
Ice caves can be considered an indicator of the long-term changes in the landscape. Ice volume is dynamic in the caves throughout the year, but the inter-seasonal comparison of ice dynamics might indicate change in the hydrological–climatic regime of ...
J. Šupinský   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Growth and motion at the Weddell Sea ice edge

open access: yes, 2007
The formation of sea ice in the presence of turbulence was studied using data from drifting buoydeployments and ice sampling in the Weddell Sea during April 2000.
Doble, Martin Jonathan
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Modelling dynamic ice-sheet boundaries and grounding line migration using the level set method

open access: yesJournal of Glaciology, 2020
Computing predictions of future sea level that include well-defined uncertainty bounds requires models that are capable of robustly simulating the evolution of ice sheets and glaciers.
M. Alamgir Hossain   +2 more
doaj   +1 more source

The optimization method of wing ice shape regulation based on flight dynamics characteristics

open access: yesScientific Reports, 2022
Ice on aircraft wing changes the aircraft aerodynamic shape, and has negative effects on flight dynamic characteristics, seriously threatening flight safety. Plasma ice shape regulation is a new de-icing method.
Pengfei Dou   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dynamic behaviour of rutford ice stream [PDF]

open access: yesAnnals of Glaciology, 1982
The grounding-line region of Rutford Ice Stream was surveyed from the ground during 1978–79 and 1979–80, and from the air in 1980–81. Maps of surface elevation and ice thickness of an area of 1 000 km2allow the grounding line to be delineated and show that the ice stream consists of several distinct fingers of thick ice trending parallel to the flow ...
Stephenson, S.N, Doake, C.S.M
openaire   +2 more sources

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