Results 71 to 80 of about 194,023 (268)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Retrieval of Cloud Macro‐Physical Properties Using theFY‐4A Advanced Geostationary Radiation Imager (AGRI) and the Geostationary Interferometric Infrared Sounder (GIIRS)

Geophysical Research Letters
This study presents a novel approach for conducting all‐day retrieval of cloud macro‐physical properties (single‐layer cloud phase, cloud top height, and cloud base height for optical thickness less than 10) using the Advanced Geostationary Radiation ...
Bin Guo, Feng Zhang, Zhijun Zhao, Jinyu Guo, Wenwen Li   +4 more
doaj   +1 more source

Challenges for Ice Age Dynamics: A Dynamical Systems Perspective [PDF]

, 2016
Contribution submitted to "Nonlinear and Stochastic Climate Dynamics", book edited by Christian L. E. Franzke (University of Hamburg, Germany) and Terence J.
Crucifix, Michel, Lenoir, Guillaume, Mitsui, Takahito   +2 more
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Thermodynamic effect dictates influence of the Atlantic Multidecadal Oscillation on Eurasia winter temperature

npj Climate and Atmospheric Science
The Atlantic Multidecadal Oscillation (AMO) has garnered attention for its important role in shaping surface air temperature (SAT) patterns over Eurasia.
Huan Wang, Zhiyan Zuo, Renhe Zhang, Li Peng, Kaiwen Zhang, Deliang Chen, Dong Xiao, Qinglong You, Guokun Dai, Ruonan Zhang, Haijun Yang, Xiaodan Chen, Zouxing Lin, Peiqiang Xu, Liang Qiao   +14 more
doaj   +1 more source

Environmental record of layers of bubbles in natural pond ice

Journal of Glaciology, 2018
Autonomous temperature data loggers were used to measure the temperature profile within a growing ice cover and in the water below. The ice formed under natural conditions over the pond.
JOLANA HRUBA, GUNTHER KLETETSCHKA
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Sea Ice Dynamics Drive Benthic Microbial Communities in McMurdo Sound, Antarctica. [PDF]

Front Microbiol, 2021
Currie AA, Marshall AJ, Lohrer AM, Cummings VJ, Seabrook S, Cary SC.   +5 more
europepmc   +1 more source