Results 111 to 120 of about 804,547 (290)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Solar Corona Structures Detection and Segmentation Using Deep Neural Networks: A Survey

IEEE Access
Image segmentation and detection of solar corona structures are a critical part of space weather applications. In recent years, deep learning-based techniques have proven to be effective for various automatic solar image processing tasks.
Peter Butka, Martin Sarnovsky, Viera Kresnakova, Simon Mackovjak, Lenka Kaliskova   +4 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Short-Term Control of Heat Pumps to Support Power Grid Operation

IEEE Open Journal of the Industrial Electronics Society
The increasing adoption of heat pumps presents new challenges for power grids, including the potential overloading of transformers and cables. To address this issue, in this work, a model predictive control for a low-temperature district heating network ...
Diran Liu, Daniele Carta, Andre Xhonneux, Dirk Muller, Andrea Benigni   +4 more
doaj   +1 more source

Método de construcción de cúpulas de hielo a partir de reforma plástica neumática [PDF]

, 2010
This thesis has presented a study into the new construction method to build ice shells with pneumatic formwork, developed at the Institute for Structural Engineering of the Vienna University of Technology.
Pérez Latorre, Juan Ignacio
core   +2 more sources

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Data Processing Approach Based on OPC UA Architecture Implementation and Bluebird Platform

IEEE Access
Process flexibility of automated workplaces, lines, and machinery is essential for optimizing, digitalizing and deploying critical principles based on IoT, IIoT and Industry 4.0/5.0.
Marek Vagas, Ondrej Majercak, Alena Galajdova, Robert Rakay, Jaroslav Romancik   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Information and Communication Technologies (ICT) for the intelligent operation of building energy systems: design, implementation and evaluation in a living lab

Energy Informatics
Successful adaptation to climate change requires resilient, reliable, and efficient energy systems. To unlock energy efficiency potentials in buildings, an intelligent, user-centered approach is vital.
Florian Redder, Philipp Althaus, Eziama Ubachukwu, Maximilian Mork, Sascha Johnen, Christian Küpper, Paul Lieberenz, Marieluise Oden, Lidia Westphal, Thomas Storek, André Xhonneux, Dirk Müller   +11 more
doaj   +1 more source

2017 State-of the Science of Dispersants and Dispersed Oil (DDO) in U.S. Arctic Waters: Physical Transport and Chemical Behavior [PDF]

, 2017
Chemical dispersants were employed on an unprecedented scale during the Deepwater Horizon oil spill in the Gulf of Mexico, and could be a response option should a large spill occur in Arctic waters. The use of dispersants in response to that spill raised
Coastal Response Research Center (CRRC)
core   +1 more source