Results 71 to 80 of about 804,547 (290)

Inorganic carbon system dynamics in landfast Arctic sea ice during the early-melt period [PDF]

, 2015
Author Posting. © American Geophysical Union, 2015. This article is posted here by permission of American Geophysical Union for personal use, not for redistribution.
Arrigo, Brown, Carnat, Chierici, Cota, Cox, Delille, Deming, Dickson, Dickson, Dieckmann, Dieckmann, Eicken, Else, Fransson, Galindo, Geilfus, Gleitz, Golden, Gosselin, IUPAC, Jones, Kennedy, Loose, Mehrbach, Melling, Miller, Miller, Mundy, Munro, Nguyen, Niemi, Nomura, Nomura, Nomura, Nomura, Nomura, Papadimitriou, Papadimitriou, Papadimitriou, Papadimitriou, Papakyriakou, Petrich, Polashenski, Pringle, Rysgaard, Rysgaard, Rysgaard, Rysgaard, Semiletov, Shirasawa, Takahashi, Thomas, Toyota, Vancoppenolle, Weiss, Zeebe, Zemmelink, Zhou   +58 more
core   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Laser-assisted explosive synthesis and transfer of turbostratic graphene-related materials for energy conversion applications

npj 2D Materials and Applications, 2022
Production of high-grade graphene-like materials using a simple, reliable processes and its simultaneous transfer onto soft surfaces have not yet achieved; hence impeding wide-ranging graphene applications.
Kapil Bhorkar, Nikolaos Samartzis, Michail Athanasiou, Labrini Sygellou, Nikos Boukos, Vassilios Dracopoulos, Theophilos Ioannides, Spyros N. Yannopoulos   +7 more
doaj   +1 more source

Oxyfuel Combustion in IC Engines

, 2023
This chapter introduces principles, mixing, ignition and combustion and controls processes of oxyfuel combustion which aims to achieve CCS (Carbon Capture and Storage) in IC (Internal Combustion) engines. By replacing air with pure oxygen and using hot and/or cooled EGR as dilutant gas for controlling the combustion process and flame speed, the mixing ...
Jun Peng, Xiang Li
openaire   +3 more sources

Frost damage and restoration of limestone domes and spheres in a heritage building [PDF]

, 2017
B
Van Bogaert, Philippe
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Source Apportionment of Fine Organic and Inorganic Atmospheric Aerosol in an Urban Background Area in Greece

Atmosphere, 2020
Fine particulate matter (PM) originates from various emission sources and physicochemical processes. Quantification of the sources of PM is an important step during the planning of efficient mitigation strategies and the investigation of the potential ...
Manousos Ioannis Manousakas, Kalliopi Florou, Spyros N. Pandis   +2 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Increasing the flexural strength of columnar-grained ice by an icy coating

Journal of Glaciology
New experiments have revealed that a thin layer of granular ice bonded to salty and to salt-free columnar-grained ice increases flexural strength when the composite material is rapidly bent to the point of failure through brittle fracture.
David Edington, Andrii Murdza, Erland M. Schulson   +2 more
doaj   +1 more source