Results 71 to 80 of about 199,393 (317)

Quantifying subglacial roughness and its link to glacial geomorphology and ice speed [PDF]

open access: yes, 2013
The shape of subglacial bed topography, termed its roughness, is a recognised control on basal ice-flow. Although glaciologists have observed patterns of variations in ice speed over beds with different roughness values, the strength of this relationship
PRESCOTT, PHILIP,WILLIAM
core  

Atmospheric ice nuclei in the Eyjafjallajökull volcanic ash plume [PDF]

open access: yes, 2011
Explosive volcanism affects weather and climate. Primary volcanic ash particles which act as ice nuclei (IN) can modify the phase and properties of cold tropospheric clouds.
B. Nillius   +29 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Reconfigurable microfluidic platform in ice [PDF]

open access: yes, 2008
Microfluidic devices are popular tools in the biotechnology industry where they provide smaller reagent requirements, high speed of analysis and the possibility for automation.
Varejka, M.
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Full-scale runback ice: accretion and aerodynamic study [PDF]

open access: yes, 2010
The runback ice phenomenon is well-known for anti-icing or de-icing systems when the system is not evaporating 100% of the water impinging the surface.
Alegre, Nathalie
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Eulerian method for ice crystal icing in turbofan engines [PDF]

open access: yes, 2017
The newer generations of high-bypass-ratio engines are susceptible to the ingestion of small ice crystals which may cause engine power loss or damage. The research presented in this thesis focusses on the development of a computational method for in-engine ice crystal accretion.
openaire   +1 more source

Ice nucleation under cirrus cloud conditions [PDF]

open access: yes, 2012
Cirrus are thin upper tropospheric clouds that are composed entirely of ice particles. Due to their extensive coverage of the Earth’s surface, they have a significant impact on the Earth’s radiative balance.
Wilson, Theodore W
core  

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