Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
How high-pressure ices on large ocean worlds can support habitability: The compatibility of amino acids into ice VI and VII. [PDF]
Hao J +9 more
europepmc +1 more source
Petermann Glacier on the brink: Progress, challenges and insights. [PDF]
Fahrner D +5 more
europepmc +1 more source
Racialized economic concentration predicts storm-related injuries and deaths in the United States, 2005-2022. [PDF]
Cheung JTH, Flingai S, Burrows K.
europepmc +1 more source
Denning Phenology Mediates Sea-Ice Loss Impacts on Early Reproductive Success in Polar Bears. [PDF]
Naciri M +6 more
europepmc +1 more source
Ice Converts Phenols into Persistent Mineral-Bound Polymers. [PDF]
Rong Y +5 more
europepmc +1 more source
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