Results 91 to 100 of about 565,318 (348)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Study on Ice Parameters Affecting DP Performance of FPSO in Arctic Ocean

open access: yes한국해양공학회지, 2018
Recently, various efforts have been made to develop oil and gas in the Arctic Ocean. It is very important to consider the load caused by ice in designing floating structures in the area.
Sol-Mi Choi   +3 more
doaj   +1 more source

Numerical modeling of ice behavior under high velocity impacts [PDF]

open access: yes, 2012
In this work a constitutive relation for ice at high strain rates and an algorithm for its numerical integra tion are developed. This model is based on the Drucker Prager plasticity criteria, which allows a different behavior in tension and in ...
López Puente, Jorge   +4 more
core   +3 more sources

Thermal ice loads on structures

open access: yesEducation and Research Archive, 1996
Structural engineering report SER 213 | SER-ID ...
Hrudey, T. M., Azarnejad, A. (Azita)
openaire   +3 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Pemakaian Thermal Storage Pada Sistem Pengkondisi Udara [PDF]

open access: yes, 1999
Air conditioning system consume 70 - 80 % of a building's energy requirement. Application of ice storage system can regulate electric load consumption so that its peak load can be ...
Sunandar, H. (Herry)   +1 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Analysis of a Collision-Energy-Based Method for the Prediction of Ice Loading on Ships

open access: yesApplied Sciences, 2019
Ships designed for operation in Polar waters must be approved in accordance with the International Code for Ships Operating in Polar Waters (Polar Code), adopted by the International Maritime Organization (IMO).
Sabina Idrissova   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Peridynamic model for submarine surfacing through ice

open access: yesZhongguo Jianchuan Yanjiu, 2018
[Objectives] With deepening research on the geographical and climatic environment of the Arctic, the political and military value of submarines in the region has been well recognized.
YE Liyu   +3 more
doaj   +1 more source

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