Results 221 to 230 of about 617,235 (290)

Quantifying and Modeling the Impact of Phase State on the Ice Nucleation Abilities of 2-Methyltetrols as a Key Component of Secondary Organic Aerosol Derived from Isoprene Epoxydiols. [PDF]

open access: yesEnviron Sci Technol
Li X   +14 more
europepmc   +1 more source

In Situ Alloying of H13 Tool Steel With TiC via PBF‐LB/M

open access: yessteel research international, EarlyView.
H13 tool steel is in situ alloyed with titanium carbides (TiC) in amounts up to 30 wt.%. This approach offers the advantage that the carbides melt only partially during processing, preventing excessive carbon enrichment of the steel matrix. The resulting microstructure consists of coarse, undissolved and fine, reprecipitated carbides, leading to grain ...
Oliver Bürgi   +2 more
wiley   +1 more source

Progress in Explosion Mechanisms and Prevention Technologies for Direct Chill Casting Aluminum Melt Upon Water Contact: A Review

open access: yesSafety Science and Technology, EarlyView.
Molten aluminum–water explosion triggered by leakage remains the core unresolved safety hazard hindering safe production in aluminum direct chill casting. This review summarizes its explosion mechanism, key influencing factors, prevention technologies, existing gaps, and prospects of intelligent multi‐technology integrated explosion‐proof systems ...
Min Wang   +5 more
wiley   +1 more source

Palaeoglaciations in the Polar and Subpolar Ural Mountains

open access: yesBoreas, EarlyView.
The Ural Mountains form a major physiographic boundary between the East European Plain and West Siberia, both repeatedly glaciated during the Pleistocene by the Barents–Kara ice sheet. Although the present‐day topography reflects significant glacial modification, the extent, chronology and interaction of mountain glaciers with the Barents–Kara ice ...
Bartosz Kurjanski   +6 more
wiley   +1 more source

α‐Synuclein strain homogeneity in multiple system atrophy subtypes

open access: yesBrain Pathology, EarlyView.
Two different subtypes of multiple system atrophy are recognized: MSA‐C and MSA‐P. In this manuscript, Lau et al. investigate whether MSA‐C and MSA‐P are caused by different strains of α‐synuclein aggregates. By performing conformational fingerprinting experiments as well as in vitro and in vivo seeding assays, their findings suggest that both MSA‐C ...
Heather H. C. Lau   +10 more
wiley   +1 more source

Monitoring Aqueous Sucrose Solutions Using Droplet Microfluidics: Ice Nucleation, Growth, Glass Transition, and Melting. [PDF]

open access: yesLangmuir
Deck LT   +6 more
europepmc   +1 more source

Directional information flow in human frataxin defines allosteric pathways connecting the hydrophobic core to the iron‐binding ridge

open access: yesThe FEBS Journal, EarlyView.
Human frataxin deficiency causes Friedreich's ataxia, yet how iron‐binding events are communicated across the protein is unclear. Using transfer entropy analysis of molecular dynamics simulations, we identify buried hydrophobic core leucines (LEU136, LEU140) as the source of directional signaling toward the iron‐binding acidic ridge.
Kevser Kübra Kırboğa   +1 more
wiley   +1 more source

A PD1‐CD137L Fusion Protein More Potently Enhances Anti‐Tumour Immune Responses Than Targeting PD‐L1 and CD137 Separately

open access: yesImmunology, EarlyView.
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia   +10 more
wiley   +1 more source

When biology meets materials science – Interdisciplinary applications of electron microscopy

open access: yesJournal of Microscopy, EarlyView.
Abstract Research at the interface between biology and materials science creates challenges for electron microscopists. Everything from the sample preparation to the choice of imaging and analytical techniques and the interpretation of the resulting data refuses to sit comfortably within the domain of one discipline or the other.
Martin Saunders   +5 more
wiley   +1 more source

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