Results 91 to 100 of about 3,442,527 (297)

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

The impact of the North American glacial topography on the evolution of the Eurasian ice sheet over the last glacial cycle [PDF]

Climate of the Past, 2016
Modeling studies have shown that the continental-scale ice sheets in North America and Eurasia in the last glacial cycle had a large influence on the atmospheric circulation and thus yielded a climate distinctly different from the present.
J. Liakka, M. Löfverström, F. Colleoni
doaj   +1 more source

Warm ocean is eroding West Antarctic Ice Sheet [PDF]

, 2004
Satellite radar measurements show that ice shelves in Pine Island Bay have thinned by up to 5.5 m yr^{-1} over the past decade. The pattern of shelf thinning mirrors that of their grounded tributaries-the Pine Island, Thwaites and Smith glaciers- and ...
Rignot, E, Wingham, Duncan, Rignot, Eric, Shepherd, Andrew, Shepherd, A, Wingham, D   +5 more
core   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

A Three-Dimensional Model of the Antarctic Ice Sheet [PDF]

Annals of Glaciology, 1988
A preliminary version of a three-dimensional ice-sheet model for later use in climate models, but excluding ice shelves and basal sliding, is presented and applied to the Antarctic ice sheet. In the model, the three-dimensional fields of velocity and temperature are calculated in the coupled mode, and the temperature equation is integrated for 150 000 ...
openaire   +2 more sources

Adsorption‐Engineered Hydrocarbon Ionomers for Durable Proton‐Exchange Membrane Fuel Cells

Advanced Materials, EarlyView.
Hydrocarbon ionomers suffer from oxidation‐driven interfacial degradation in PEM fuel cell cathodes, leading to catalyst instability. Here, adsorption‐engineered poly(fluorene) ionomers decouple interfacial anchoring from oxidative degradation, enabling strong catalyst–ionomer interactions while resisting electrochemical oxidation.
Heemin Park, Kate Chen, Su Min Ahn, Hengquan Guo, Cy Fujimoto, Jong‐Ho Choi, Lynda Amichi, Danah Kim, Seung Geol Lee, Xiaojing Wang, Jacob S. Spendelow, Sun Young Kang, Panagiotis Bexis, Eun Joo S. Park, Yu Seung Kim   +14 more
wiley   +1 more source

Estimation of glacier ice extinction using long-wavelength airborne Pol-InSAR [PDF]

, 2013
In recent years there has been increased interest in using synthetic aperture radar (SAR) to study and monitor glaciers and ice sheets for glaciological and climate change research.
Sharma, Jayanti, Hajnsek, Irena, Moreira, Alberto, Papathanassiou, Konstantinos   +3 more
core   +1 more source

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Confinement‐Induced Donnan Potential Enables Sealed Hydrovoltaic Power From Microliter Water

Advanced Materials, EarlyView.
An ultrathin MXene/cellulose nanofiber (CNF) nanochannel‐based hydrovoltaic generator produces sustained direct current (DC) from a single microliter droplet under sealed operation. Asymmetric nanochannel confinement establishes a persistent ion gradient and a confinement‐induced Donnan potential, harvesting the interfacial free energy released upon ...
Sangyun Na, Geonyoung Jung, Yoojin Chang, Yun Goo Ro, Cheolhong Park, Jeonghee Yeom, Jinyoung Kim, Jeeyoon Kim, Hyejin Lee, Hyeji Oh, Hyunhyub Ko   +10 more
wiley   +1 more source

A synthesis of the basal thermal state of the Antarctic ice sheet

Journal of Glaciology
The basal thermal state of the Antarctic ice sheet (AIS)—whether the base is frozen or thawed—fundamentally underpins its flow and is an important factor in understanding its large-scale response to external forcings.
Owen Seiner, Anna Hugney, Hélène Seroussi, Joseph A MacGregor   +3 more
doaj   +1 more source