Results 61 to 70 of about 3,442,527 (297)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A model of the Antarctic Ice Sheet

Deep Sea Research Part B. Oceanographic Literature Review, 1982
Numerical modelling of ice sheets and glaciers has become a useful tool in glaciological research. A model described here deals with the vertical mean ice velocity, is time dependent, computes bedrock adjustment and uses an empirical diagnostic relationship to derive the distribution of ice thickness in ice shelves.
openaire   +3 more sources

Recent Progress in Greenland Ice Sheet Modelling [PDF]

Current Climate Change Reports, 2017
This paper reviews the recent literature on numerical modelling of the dynamics of the Greenland ice sheet with the goal of providing an overview of advancements and to highlight important directions of future research. In particular, the review is focused on large-scale modelling of the ice sheet, including future projections, model parameterisations,
Heiko Goelzer, Alexander Robinson, Helene Seroussi, Roderik S.W. van de Wal   +3 more
openaire   +6 more sources

Trimlines, blockfields and the vertical extent of the last ice sheet in southern Ireland [PDF]

, 2015
The research reported here was supported by UK NERC grant NER/B/S/2001/0919Trimlines separating glacially abraded lower slopes from blockfield-covered summits on Irish mountains have traditionally been interpreted as representing the upper limit of the ...
Stone, John O., John O. Stone, Ballantyne, Colin, Colin K. Ballantyne   +3 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Influence of ice-sheet geometry and supraglacial lakes on seasonal ice-flow variability [PDF]

The Cryosphere, 2013
Supraglacial lakes play an important role in establishing hydrological connections that allow lubricating seasonal meltwater to reach the base of the Greenland Ice Sheet.
I. Joughin, S. B. Das, G. E. Flowers, M. D. Behn, R. B. Alley, M. A. King, B. E. Smith, J. L. Bamber, M. R. van den Broeke, J. H. van Angelen   +9 more
doaj   +1 more source

Potential subglacial lake locations and meltwater drainage pathways beneath the Antarctic and Greenland ice sheets [PDF]

, 2013
We use the Shreve hydraulic potential equation as a simplified approach to investigate potential subglacial lake locations and meltwater drainage pathways beneath the Antarctic and Greenland ice sheets. We validate the method by demonstrating its ability
Clark, Chris, Woodward, J., Livingstone, Stephen, Woodward, John, Clark, C.D., Kingslake, J., Livingstone, S.J., Livingstone, S. J., Clark, C. D., J. Kingslake, Kingslake, Jonathan, C. D. Clark, S. J. Livingstone, J. Woodward   +13 more
core   +2 more sources

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

WAVI.jl: Ice Sheet Modelling in Julia

Journal of Open Source Software
Ice sheet models are used to improve our understanding of the past, present, and future evolution of ice sheets. To do so, they solve the equations describing the flow of ice when forced by other climate elements, particularly the atmosphere and oceans. We present WAVI.jl, an ice sheet model written in Julia.
Alexander T. Bradley, Robert J. Arthern, David T. Bett, C. Rosie Williams, James Byrne   +4 more
openaire   +3 more sources

Reconstruction of ice-sheet changes in the Antarctic Peninsula since the Last Glacial Maximum [PDF]

, 2014
This paper compiles and reviews marine and terrestrial data constraining the dimensions and configuration of the Antarctic Peninsula Ice Sheet (APIS) from the Last Glacial Maximum (LGM) through deglaciation to the present day.
Glasser, N.F., Davies, Bethan J., Emma P. Hocking (7190990), Larter, Robert D., Larter, R.D., Anderson, J.B., John B. Anderson (7190993), Livingstone, Stephen J., Simms, A.R., Roberts, S.J., Ó Cofaigh, Colm, Domack, E., Evans, J., Hillenbrand, Claus-Dieter, James A. Smith (1496818), Livingstone, Stephen, Michael J. Bentley (7190996), Livingstone, S.J., Dowdeswell, Julian, Anderson, John B., Hocking, Emma, Eugene Domack (6507515), Anderson, John, Canals, M., Canals, Miquel, Roberts, Stephen J., Johnson, J.S., O Cofaigh, C., Stephen J. Roberts (7191008), Hillenbrand, C.D., Larter, Robert, Simms, Alexander, Neil F. Glasser (7191002), Hodgson, Dominic A., Smith, J.A., Julian A. Dowdeswell (7190999), Bentley, Michael J., Colm O Cofaigh (7190984), Jeffrey Evans (1254507), Dowdeswell, Julian A., Hocking, Emma P., Simms, Alexander R., Hillenbrand, Claus Dieter, Hodgson, D.A., Smith, James A., Bentley, M.J., Domack, Eugene, Dowdeswell, J.A., Davies, Bethan, Alexander R. Simms (7191011), Stephen J. Livingstone (3691018), Joanne S. Johnson (7190987), Robert D. Larter (7191005), Johnson, Joanne S., Bentley, Michael, Hodgson, Dominic, Bethan J. Davies (2843855), Glasser, Neil, Miquel Canals (186525), Claus-Dieter Hillenbrand (4276453), Dominic A. Hodgson (2043412), Evans, Jeffrey, Glasser, Neil F., Hillenbrand, C-D., Canals, Miguel, Hocking, E.P., Davies, B.J.   +66 more
core   +1 more source