On‐Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles
A microfluidic platform integrates mRNA synthesis, purification, and LNPs formulation in a continuous, streamlined process. DNA templates are transcribed on‐chip, producing mRNA that is immediately purified and encapsulated into LNPs. This approach enables rapid, scalable production of mRNA‐LNP formulations for research or therapeutic applications ...
Shai Zilberzwige‐Tal+13 more
wiley +1 more source
Marine Anoxia and Ocean Acidification During the End‐Permian Extinction
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Ying Cui+4 more
wiley +4 more sources
Satellite record reveals 1960s acceleration of Totten Ice Shelf in East Antarctica. [PDF]
Li R+10 more
europepmc +1 more source
Chemical Profile of the Ross Ice Shelf at Little America V, Antarctica [PDF]
Chester C. Langway+2 more
openalex +1 more source
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai+5 more
wiley +1 more source
A modular hybrid membrane is constructed via a layer‐by‐layer strategy, integrating glucose oxidase/horseradish peroxidase or glucose oxidase/nanozyme‐loaded microreactors within alternating polyelectrolyte layers on a calcium carbonate core. This hierarchical design enables precise spatial confinement of catalytic units, facilitating efficient cascade
Aitor Ontoria+7 more
wiley +1 more source
Ross Ice Shelf Displacement and Elastic Plate Waves Induced by Whillans Ice Stream Slip Events
Ice shelves are assumed to flow steadily from their grounding lines to the ice front. We report the detection of ice‐propagating extensional Lamb (plate) waves accompanied by pulses of permanent ice shelf displacement observed by co‐located Global ...
Douglas A. Wiens+5 more
doaj +1 more source
Petermann ice shelf may not recover after a future breakup. [PDF]
Åkesson H+4 more
europepmc +1 more source
Is Vertical Shear in an Ice Shelf Negligible? [PDF]
T. J. O. Sanderson, C. S. M. Doake
openalex +1 more source