Results 61 to 70 of about 791,243 (256)

Oral Recombinant Human Collagen III Protects Gastric Mucosa via G‐Quadruplex‐Mediated Activation of the Pla2g4a‐Prostaglandin Axis

Advanced Science, EarlyView.
Orally administered recombinant human type III collagen protects the gastric mucosa from ethanol‐induced injury by coordinating redox homeostasis, epithelial barrier repair, and arachidonic acid–prostaglandin metabolism. Gastric digestion releases the pentapeptide GPAEF, which interacts with the Pla2g4a promoter G‐quadruplex in a structure‐dependent ...
Xinyue Lan, Qiu Dai, Yanhui Wang, Jiaxuan Gu, Chengyun Wang, Weicheng Xu, Xinru Gao, Jiageng Cheng, Wentao Geng, Xiaowen Wu, Haihang Li, Xiaoyun He, Shengwei Fu, Longjiao Zhu, Wentao Xu   +14 more
wiley   +1 more source

The speedup of Pine Island Ice Shelf between 2017 and 2020: revaluating the importance of ice damage

Journal of Glaciology, 2023
From 2017 to 2020, three significant calving events took place on Pine Island Glacier, West Antarctica. Ice-shelf velocities changed over this period and the calving events have been suggested as possible drivers.
Sainan Sun, G. Hilmar Gudmundsson
doaj   +1 more source

Influence of the future surface meltwater from the Antarctic ice sheet on the Southern Ocean properties and ice-shelf basal melt

, 2023
The Antarctic ice sheet mass loss is one of the many consequences of Global Warming. This mass loss is primarily driven by ocean warming and the subsequent acceleration of glaciers.
Mathiot, Pierre, Kittel, Christoph, Jourdain, Nicolas C., Coulon, Violaine   +3 more
core  

CTD profiles from beneath Ekstroem Ice Shelf and Atka Bay

, 2020
CTD profiles of the water column beneath Ekstroem Ice Shelf and the adjacent Atka Bay. Ice shelf profiles were made through hot-water drilled access holes in the ice sheld and the profile in Atka Bay was taken through a sea-ice lead.
Tiedemann, Ralph, Tell, Jan, Kuhn, Gerhard, Berger, Sophie, Haas, Christian, Hattermann, Tore, Gaedicke, Christoph, Eisen, Olaf, Smith, Emma Clare, Gromig, Raphael, Tison, Jean-Louis, Wilhelms, Frank, Läufer, Andreas   +12 more
core   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

Advanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang, Lun Zhu, Ze Sun, Ruolin Jia, Ziming Wang, Jiayao Zhao, Bohao Liu, Haiqing Xiong, Xiaowei Yu, Yanzhu Yue   +9 more
wiley   +1 more source

Past and future dynamics of the Brunt Ice Shelf from seabed bathymetry and ice shelf geometry [PDF]

The Cryosphere, 2019
The recent rapid growth of rifts in the Brunt Ice Shelf appears to signal the onset of its largest calving event since records began in 1915. The aim of this study is to determine whether this calving event will lead to a new steady state in which the ...
D. A. Hodgson, D. A. Hodgson, T. A. Jordan, J. De Rydt, P. T. Fretwell, S. A. Seddon, S. A. Seddon, D. Becker, K. A. Hogan, A. M. Smith, D. G. Vaughan   +10 more
doaj   +1 more source

TanDEM-X ice thickness dataset for Wilkins Ice Shelf, Antarctic Peninsula, with link to GeoTIFF

, 2015
The dataset shows the ice thickness over Wilkins Ice Shelf, Antarctic Peninsula derived from TanDEM-X Interferometry. The data has been acquired between June and August 2012. The TanDEM-X heights have been linked to CryoSAT-2 heights (V.
Rankl, Melanie, Helm, Veit, Braun, Matthias Holger   +2 more
core   +1 more source

The ocean's forcing on the ice shelf of Petermann Gletscher, Greenland

, 2020
Muenchow, AndreasNicholls, Keith W.Petermann Gletscher is a large outlet glacier in northwest Greenland that transports 4% of the ice sheet into Petermann Fjord.
Washam, Peter
core   +1 more source

Sustainable Hydrogel‐Forming Microneedle‐Reservoir Patches for Transdermal Delivery of Hydrophilic Macromolecules: Biopolymers, Green Manufacturing and Translation

Advanced Science, EarlyView.
Hydrogel‐forming microneedle (HFMN)‐reservoir patches provide a modular route for controlled transdermal delivery of hydrophilic biomacromolecules. The platform integrates skin‐barrier penetration, sustainable biopolymers, scalable green manufacturing, hydration‐driven transport, model‐cargo validation, and translational quality requirements.
Siddharth Mohanty, Mehmet Onur Aydogdu, Sijia Kang, Xinbo Li, Mohan Edirisinghe   +4 more
wiley   +1 more source

The details of how to implement and apply sub-shelf melt parametrizations in standalone ice sheet models - Does it matter for Antarctic sea level projections?

, 2023
Sub-shelf melting is the main driver of current Antarctic mass loss. However, the ocean processesgoverning ice shelf melting are not well understood and sub-shelf melt is currently themain uncertainty source within Antarctic sea level projections ...
Zipf, Lars, Pattyn, Frank, Coulon, Violaine   +2 more
core