Results 131 to 140 of about 588,382 (370)

Review "Evaluation of four calving laws for Antarctic ice shelves"

, 2023
Javier Blasco
openalex   +1 more source

Variation in the seston C:N ratio of the Arctic Ocean and pan-Arctic shelves [PDF]

, 2014
Studying more than 3600 observations of particulate organic carbon (POC) and particulate organic nitrogen (PON), we evaluate the applicability of the classic Redfield C:N ratio (6.6) and the recently proposed Sterner ratio (8.3) for the Arctic Ocean and ...
Andersen, Tom, Bellerby, Richard G. J., Frigstad, Helene, Hessen, Dag O., Silyakova, Anna   +4 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

SNOWPACK simulations forced by MERRA-2 for Antarctic Ice Shelves

, 2023
Wever
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

A high-resolution record of surface melt on Antarctic ice shelves using multi-source remote sensing data and deep learning

, 2023
Sophie de Roda Husman, Stef Lhermitte, Jordi Bolíbar, Maaike Izeboud, Zhongyang Hu, Shashwat Shukla, Marijn van der Meer, David G. Long, Bert Wouters   +8 more
openalex   +1 more source

Intercomparison of Antarctic ice-shelf, ocean, and sea-ice interactions simulated by MetROMS-iceshelf and FESOM 1.4 [PDF]

, 2018
An increasing number of Southern Ocean models now include Antarctic ice-shelf cavities, and simulate thermodynamics at the ice-shelf/ocean interface. This adds another level of complexity to Southern Ocean simulations, as ice shelves interact directly ...
Debernard, Jens B., England, Matthew H., Galton-Fenzi, Benjamin K., Hattermann, Tore, Hellmer, Hartmut H., Meissner, Katrin J., Naughten, Kaitlin A., Timmermann, Ralph   +7 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Rheological control of crystal fabrics on Antarctic ice shelves

Journal of Glaciology
Ice crystal fabrics can exert significant rheological control on ice sheets and ice shelves, potentially softening or hardening anisotropic ice by several orders of magnitude compared to isotropic ice. We introduce an anisotropic extension of the Shallow
Nicholas M. Rathmann, David A. Lilien, Daniel H. Richards, Felicity S. McCormack, Maurine Montagnat   +4 more
doaj   +1 more source

Late Pleistocene glacial terminations accelerated by proglacial lakes [PDF]

Climate of the Past
During the glacial cycles of the past 800 000 years, Eurasia and North America were periodically covered by large ice sheets, causing up to 100 m of sea-level change.
M. D. W. Scherrenberg, C. J. Berends, R. S. W. van de Wal, R. S. W. van de Wal   +3 more
doaj   +1 more source