Results 141 to 150 of about 588,382 (370)

Influence of ocean tides and ice shelves on ocean–ice interactions and dense shelf water formation in the D’Urville Sea, Antarctica

, 2021
Pierre-Vincent Huot, Thierry Fichefet, Nicolas C. Jourdain, Pierre Mathiot, Clément Rousset, Christoph Kittel, Xavier Fettweis   +6 more
openalex   +2 more sources

Fracture Mechanical Analysis of Cracks in Ice Shelves using the Finite Element Method and Configurational Forces [PDF]

, 2011
Ice shelves are important elements of the climate system and sensitive to climate changes. The disintegration of large Antarctic ice shelves is the focus of this fracture mechanical analysis. Ice is a complex material which, depending on the context, can
Gross, Dietmar, Humbert, Angelika, Müller, Ralf, Plate, Carolin   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Actively evolving subglacial conduits and eskers initiate ice shelf channels at an Antarctic grounding line [PDF]

, 2017
Ice-shelf channels are long curvilinear tracts of thin ice found on Antarctic ice shelves. Many of them originate near the grounding line, but their formation mechanisms remain poorly understood.
A Jenkins, AM Le Brocq, B Hubbard, CH Dix, CV Gladish, D Callens, DG Vaughan, E Rignot, E Rignot, F Pattyn, FSL Ng, FSL Ng, GH Gudmundsson, H Röthlisberger, HJ Horgan, J Lenaerts, J Walder, JA Dowdeswell, JF Nye, JJ Fürst, K Christianson, K Matsuoka, KE Alley, L Favier, MC Dallaston, MJ Burke, MJ Fried, O Gagliardini, OJ Marsh, OV Sergienko, P Defraigne, P Dutrieux, P Fretwell, PU Clark, R Bindschadler, R Drews, R Drews, RB Alley, RL Hooke, RL Shreve, RS Taylor, RT Walker, RW Jacobel, S Berger, S Fujita, SJ Livingstone, SJ Livingstone, T Cowton, T Millgate, TA Brennand, TP Stanton, TR Davies, TRH Davies, V Helm   +53 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Contrasting optical properties of dissolved organic matter between oceanic regions near the Getz and Dotson ice shelves in the Amundsen Sea, West Antarctica

, 2023
Juyoung Son, Jinyoung Jung, Youngju Lee, Tae‐Wan Kim, Jisoo Park, Mi Hae Jeon, Mi Ok Park   +6 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Antarctic ice-shelf meltwater outflows in satellite radar imagery: ground-truthing and basal channel observations

Journal of Glaciology
Ice shelves regulate the flow of the Antarctic ice sheet toward the ocean and its contribution to sea-level rise. Accurately monitoring the basal and surface melting of ice shelves is therefore essential for predicting the ice sheet's response to ...
Jakob Stanley Hamann, Thomas Arney, James David Kirkham, Paul Wachter, Karsten Gohl   +4 more
doaj   +1 more source

Effective Rheology Across the Fragmentation Transition for Sea Ice and Ice Shelves

Geophysical Research Letters, 2019
Sea ice and ice shelves can be described by a viscoelastic rheology that is approximately linear elastic and brittle at high strain rates and viscously shear thinning at low strain rates.
J. Åström, D. Benn
semanticscholar   +1 more source

Seasonal and spatial variations in the ocean-coupled ambient wavefield of the Ross Ice Shelf [PDF]

, 2019
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Baker, M. G., Aster, R. C., Anthony, R. E., Chaput, J., Wiens, D. A., Nyblade, A., Bromirski, P.
Anthony, Robert E., Aster, Richard C., Baker, Michael G., Bromirski, Peter D., Chaput, Julien, Gerstoft, Peter, Nyblade, Andrew A., Stephen, Ralph A., Wiens, Douglas A.   +8 more
core   +1 more source